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"🧬 vs. 🌍: How Genetics and the Exposome Shape Aging & Mortality ⏳⚰️"

"🧬 vs. 🌍: How Genetics and the Exposome Shape Aging & Mortality ⏳⚰️"

Dr RR Baliga's "Got Knowledge Doc" Podkast

March 3, 20252m 50s

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Show Notes

This study explores how environmental exposures (exposome) 🌍 and genetics 🧬 contribute to aging ⏳ and mortality ⚰️.

Using UK Biobank data 📊, researchers found that the exposome explains 17% of mortality risk, while genetics accounts for only 2%.

Smoking 🚬, socioeconomic status 💰, and physical activity 🏃‍♂️ are major environmental influences, whereas genetics plays a stronger role in dementia 🧠 and cancers 🦠.

The findings highlight the need for public health policies 🏥 targeting modifiable lifestyle factors over genetic interventions.