
⚙️ The Operating System of Cancer: Hallmarks, Enablers, Ecosystems
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🧠🩺 Why cancers behave the way they do—and why treatments fail
For internists, cancer is not just an oncologic diagnosis but a systems disease: driven by dysregulated growth, immune evasion, metabolic reprogramming, inflammation, and adaptive resistance.
The Hallmarks of Cancer framework offers a unifying clinical lens—explaining recurrence, cachexia, immunotherapy variability, and late relapse—without drowning us in molecular minutiae.
Understanding how tumors survive stress, therapy, and time sharpens prognosis, improves cross-disciplinary care, and strengthens bedside reasoning.
🔬 From biology to bedside. 🧩 From mechanisms to meaning. 📈 From treatment to trajectory.