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πŸ”¬ Silence APOC3, Slash Triglycerides, A New Era in Triglyceride Control

πŸ”¬ Silence APOC3, Slash Triglycerides, A New Era in Triglyceride Control

Dr RR Baliga's "Got Knowledge Doc" Podkast

September 16, 20254m 42s

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Show Notes

🚨 New NEJM Study on Olezarsen 🚨

In patients with moderate hypertriglyceridemia and elevated cardiovascular risk, monthly subcutaneous olezarsen reduced triglycerides by over 60% at 6 months! πŸ“‰πŸ’₯

βœ… Significant drops in APOC3, VLDL, remnant & non-HDL cholesterol

βœ… No rise in LDL-C

βœ… Well-tolerated with mild injection-site reactions

πŸ”¬ APOC3 inhibition emerges as a game-changer in lipidology.

πŸ“– ESSENCE–TIMI 73b Trial | Funded by Ionis Pharmaceuticals

#Cardiology #LipidLowering #PrecisionMedicine #NEJM #Olezarsen #TGlowering #CVRisk #TIMI #Atherosclerosis #GenomicTherapy πŸ§¬πŸ’ŠπŸ«€