🧬 Omega-3, Vitamin D & Exercise: Slowing Biological Aging – Insights from the DO-HEALTH Trial 🏋️♂️💊
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🔬 DO-HEALTH Trial Summary 🏋️♂️💊🧬
A randomized controlled trial (RCT) with 777 participants aged 70+ investigated the effects of omega-3 (🧴 1g/day), vitamin D (☀️ 2000 IU/day), and exercise (🏃♂️ 30 min, 3x/week) on biological aging using DNA methylation clocks.
📊 Key Findings:
✅ Omega-3 alone slowed biological aging by 2.9–3.8 months over 3 years.
✅ Combined interventions further reduced biological aging and improved health outcomes.
✅ Health benefits: 🔽 10% fall reduction, 🦠 13% lower infection rates, 💪 39% less prefrailty, 🛡️ 61% lower invasive cancer risk.
🔍 Conclusion: Omega-3, vitamin D, and exercise may slow biological aging and enhance healthspan. Further research is needed to assess long-term benefits. 🚀