
🦷 "Mouth to Myocardium to Mortality: How Oral Bacteria Hijack the Heart"
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🦷🫀 New Findings Linking Oral Health to Heart Attacks! 🧬🧫
Groundbreaking research in JAHA reveals that viridans streptococci, common oral bacteria, form biofilms in atherosclerotic plaques that evade immune detection.
These stealthy invaders trigger innate and adaptive immune responses, correlating with plaque rupture, myocardial infarction, and sudden cardiac death.
The study combines autopsy data, endarterectomy samples, immunohistochemistry, TLR activation assays, and genome-wide expression to uncover this bacterial-inflammation nexus.
🧠 Could dental hygiene be the next frontier in cardiovascular prevention?
📖 Karhunen et al. JAHA. 2025;14:e041521
🔗 #Cardiology #Immunology #OralHealth #Atherosclerosis #Biofilm #PrecisionMedicine #JAHA #DentalHealth #SuddenCardiacDeath #MultiOmics #CHD #ViridansStreptococci #PlaqueRupture #InnateImmunity #AdaptiveImmunity #TLR2 #NFkB #Streptococcus #MI #Endarterectomy