
๐ฅ Modern PCI, ๐ซ MI Managed, ๐ Aspirin Dropped Early, ๐ Bleeds Reduced
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
๐ก TARGET-FIRST trial (NEJM, Aug 2025) shows that in low-risk AMI patients post-PCI with complete revascularization, stopping aspirin after 1 month and continuing P2Y12 monotherapy is noninferior to dual antiplatelet therapyโwith 54% fewer bleeding events ๐ฉธ๐๐
โ๏ธ A modern, patient-tailored antiplatelet strategyโbacked by potent P2Y12 inhibitors and smart selectionโmight just be the new norm in contemporary cardiology ๐ซ
๐ New England Journal of Medicine
๐ https://doi.org/10.1056/NEJMoa2508808
#Cardiology #DAPT #PrecisionMedicine #NEJM #TARGETFIRST