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HCM in Two Acts 🎭: Aficamten, Mavacamten & Dueling Data in the Quest to Tame HCM

HCM in Two Acts 🎭: Aficamten, Mavacamten & Dueling Data in the Quest to Tame HCM

Dr RR Baliga's "Got Knowledge Doc" Podkast

September 20, 20257m 8s

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Show Notes

🚨 New Podcast Drop! 🎙️

"Myosin, Metrics & Momentum 🧬📈🫀" dives into 3 landmark NEJM articles on Aficamten vs Mavacamten in hypertrophic cardiomyopathy.

We decode:

🔹 MAPLE-HCM (obstructive HCM)

🔹 ODYSSEY-HCM (nonobstructive HCM)

🔹 Expert editorial insights on PROs, EF, & trial design

🎯 Learn what matters: peak VO₂ vs PROs, safety signals, and the road ahead in precision cardiomyopathy care.

🎧 Tune in and share! #HCM #CardioTwitter #NEJM #HeartFailure #MyosinInhibitors #Podcast