
π Genes, Gradients, and Game-Changers: FAQs on Hypertrophic Cardiomyopathy
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
π§ Hypertrophic Cardiomyopathy β A Masterclass from Eugene Braunwald π§¬
π Just published in NEJM (Aug 2025): a sweeping, state-of-the-art review on HCM β from Teare's first autopsy to myosin inhibitors, AI diagnostics, and gene therapy.
π₯ Clinical insights, historical depth, trial data (EXPLORER-HCM, SEQUOIA-HCM, VALOR-HCM), and future-facing advancesβall distilled into one must-read.
π SCD prevention, π« LVOT obstruction, π§ͺ MYBPC3/MYH7 mutations, 𧬠proteomics, and more.
π Essential reading for cardiologists, geneticists, and translational scientists.
#HCM #Braunwald #NEJM #Cardiology #PrecisionMedicine #Mavacamten #Aficamten #GeneTherapy #MedicalEducation #SCDprevention