From Mom or Dad? It Makes a Difference whether Growth or Metabolsim 🤔👩🍼👨🍼
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🚀 New in Nature: Groundbreaking study reveals how the origin of your genes — from mom 👩🍼 or dad 👨🍼 — can push human growth 📏 and metabolism 🔥 in opposite directions!
🧬 Using data from 236,781 people across UK Biobank, Estonian Biobank, and MoBa, researchers uncovered 30+ parent-of-origin effects (POEs), many showing bipolar impacts — boosting traits when inherited from one parent, reducing them from the other.
⚖️ Findings support the parental conflict hypothesis: paternal genes tend to promote growth 🚀, while maternal genes conserve resources 🛡️. These insights were invisible to standard GWAS, proving the power of family-rich biobanks in unlocking hidden genetic layers.
🔗 Read the paper: https://doi.org/10.1038/s41586-025-09357-5
#Genomics #GWAS #Biobanks #ParentOfOrigin #Growth #Metabolism #PrecisionMedicine