From Gene to Lipid to Clinic: The Rise of RNA Therapies
Dr RR Baliga's "Got Knowledge Doc" Podkast
October 5, 20256m 32s
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Show Notes
🚨 New NEJM study highlights a breakthrough in triglyceride management! 🧬 In the ESSENCE–TIMI 73b trial, monthly subcutaneous olezarsen targeting APOC3 cut triglycerides by ~60% at 6 months 📉—with strong safety and nearly 90% reaching normal TG levels.
A promising step in precision lipid therapy! 💉🫀 #Lipidology #RNAtherapeutics #Cardiology #NEJM #Olezarsen #APOC3