🧬🔬 From Barnyard to Human Chest: 216 Hours of Pig Lung in Man
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🐖🫁 World First: Pig Lung Transplanted into Human 🧬🌍
In a groundbreaking step for xenotransplantation, a team in China successfully transplanted a genetically modified pig lung into a brain-dead human recipient. The lung functioned for 216 hours without hyperacute rejection, offering hope to thousands on organ waitlists.
🔬 Key breakthroughs:
• 6-gene-edited donor pig
• No Porcine Endogenous Retrovirus (PERV-C) detected 🦠
• Controlled immune response 🛡️
• PGD observed but stabilized 💉
📖 Published in Nature Medicine: https://doi.org/10.1038/s41591-025-03861-x
👏 A monumental leap toward clinical trials and saving lives.
#Xenotransplantation #LungTransplant #OrganDonation #Immunology #PrecisionMedicine #NatureMedicine #TranslationalScience 🚀