💥 Force, Fibroblasts & 🫀 Failure
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🚨 New Insights in Dilated Cardiomyopathy (DCM)! 🫀
Fibroblasts aren't just bystanders — they're mechanical rheostats shaping disease severity. 🧬
This groundbreaking study shows that blocking p38 signaling halts fibrosis, boosts contractility, and may redefine how we treat DCM. 💥
🧠 Think beyond myocytes. Think collective cell behavior.
🧪 Read the full paper in Science:
"Preventing Hypocontractility-Induced Fibroblast Expansion Alleviates DCM"
#Cardiology #HeartFailure #Fibrosis #ECM #PrecisionMedicine #Fibroblasts #DCM #p38MAPK #HeartResearch #TranslationalMedicine 🧵