ENaC ⚙️ RAAS ⚡ Immunity 🧬: The Gender Divide in Hypertension
Dr RR Baliga's "Got Knowledge Doc" Podkast
August 17, 20258m 45s
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Show Notes
🧂 Salt sensitivity of blood pressure (SSBP) is an independent risk factor for CVD.
🚹🚺 Women are more salt-sensitive than men, especially after menopause.
⚙️ Key drivers: RAAS, ENaC, natriuresis, and immune pathways.
💉 Estrogen protects, testosterone raises pressure, menopause tips the balance.
🐀 From Dahl's rats to Conn's syndrome, SSBP research shows why sex-specific, personalized therapy is the future of hypertension care.
🔗 Nature Reviews Cardiology