🎯 Early Aspirin Withdrawal After PCI in ACS is Risky?
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🧪 NEO-MINDSET Trial 🇧🇷 published in NEJM asks: Can we safely drop aspirin early after PCI in acute coronary syndromes (ACS)?
💊 Monotherapy with ticagrelor/prasugrel reduced bleeding 🩸 but increased early ischemic events 💥 vs dual antiplatelet therapy (DAPT).
❗ Noninferiority for major adverse cardiovascular events was not met.
🔍 DAPT still stands tall in early post-PCI ACS care.
Kudos to the Brazilian team for a landmark RCT!
📖 NEJM 2025 | doi: 10.1056/NEJMoa2507980
#NEOMINDSET #PCI #ACS #cardiotwitter #RCT #DAPT #P2Y12 #Bleeding #NEJM #PrecisionMedicine #InterventionalCardiology