🫀 Coronary Artery Bypass Blues: Does Lower LDL-C Save the Venous Graft?
Dr RR Baliga's "Got Knowledge Doc" Podkast
September 24, 20254m 58s
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Show Notes
🫀 NEWTON-CABG Trial: Can intensive LDL-C lowering prevent vein graft failure after CABG?
💉 Evolocumab slashed LDL-C by ~50%, but did not improve SVG patency at 2 years. Why? Timing is everything.
🧠 Early SVG failure = thrombosis & hyperplasia—not classic atherosclerosis. LDL-C ≠ magic bullet here.
#Cardiology #CABG #LDL #PCSK9 #Evolocumab #CardioTrials #Lipids #HeartHealth #GraftPatency #ClinicalResearch #JACC #TheLancet #SurgeryMeetsPrevention