
Chronic lymphedema may not just be about fluid. It may be about cholesterol. 🧬
Dr RR Baliga's "Got Knowledge Doc" Podkast
February 16, 20266m 5s
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Show Notes
Chronic lymphoedema may not just be about fluid. It may be about cholesterol. 🧬
In human tissue and translational mouse models, impaired lymphatic drainage led to excess dermal cholesterol deposition, adipocyte dysfunction, fibrosis, and swelling — even when plasma cholesterol was normal.
Clearing tissue cholesterol with cyclodextrin restored lymphatic architecture and reduced oedema.
Clear the cholesterol. Restore the flow