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๐Ÿ’Š Block. Beat. Benefit. The Hidden Strength of ฮฒ-Blockers Post-MI

๐Ÿ’Š Block. Beat. Benefit. The Hidden Strength of ฮฒ-Blockers Post-MI

Dr RR Baliga's "Got Knowledge Doc" Podkast

September 1, 20254m 3s

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Show Notes

๐Ÿšจ New Meta-Analysis Alert! ๐Ÿ’Š๐Ÿซ€

Can ฮฒ-blockers benefit patients post-MI with mildly reduced ejection fraction (LVEF 40โ€“49%)?

๐Ÿ“Š An individual patient data meta-analysis (REBOOT, BETAMI, DANBLOCK, CAPITAL-RCT) shows a 25% reduction in the composite outcome of death, MI, or HF with ฮฒ-blockers vs. control (HR 0.75; p=0.031) โ€” even in the absence of clinical heart failure.

๐ŸŒ Consistent across trials and countries. Most benefit seen in patients

๐Ÿ“š This could shift guidelines for a large overlooked population.

๐Ÿ”— Read more in The Lancet (Aug 30, 2025)

#Cardiology #BetaBlockers #MyocardialInfarction #LVEF #EvidenceBasedMedicine #MetaAnalysis #HeartHealth ๐Ÿ’“๐Ÿ“‰