Biomarkers, Big Data & Biology: Mapping the Plasma Proteome Across 59 Diseases
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🧬 New Era in Blood-Based Biomarkers! 🩸
A pan-disease atlas of the circulating proteome across 59 diseases and 8,262 individuals reveals powerful insights into age, sex, BMI, and disease-specific protein signatures.
💡 Highlights:
🔹 Over 5,400 proteins profiled using Olink
🔹 Longitudinal stability of wellness proteome
🔹 Machine learning predicts biological age (R² = 0.85)
🔹 Shared vs disease-specific profiles across conditions
🔹 Early signals in cancers like lung and ovarian 🎯
📍 Explore the resource: proteinatlas.org/humanproteome/blood
📖 Read the study in Science: https://doi.org/10.1126/science.adx2678
#Proteomics #PrecisionMedicine #Biomarkers #MultiOmics #HumanProteinAtlas #BloodAtlas #EarlyDetection #SystemsBiology #Cardiology #Oncology #MachineLearning 🧠🔍📊