Beyond Cholesterol 🌪️: 🇮🇳🩺: Lp(a)'s Reach in the South Asian Diaspora
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🔬 New Review Alert! 🫀
South Asians face one of the highest global burdens of premature heart disease — and Lp(a) may be the silent culprit. 📈 In a comprehensive JAHA 2025 review, researchers reveal how 25% of South Asians have dangerously elevated Lp(a) levels, doubling their risk of myocardial infarction. 🧬💥
Key takeaways:
✅ Lp(a) is genetically driven & unaffected by lifestyle
✅ Risk is underestimated by standard calculators
✅ Novel therapies (PCSK9i, siRNA, ASOs) are on the horizon
✅ One-time testing is now strongly recommended in all South Asians 🧪
📚 Based on INTERHEART, UK Biobank, PROMIS, and MASALA — this is a must-read for anyone tackling health disparities in cardiology.