Beta Blockers in MI: Old Drug, New Lens, Possible Win 🔍💥🏥
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🚨 New NEJM Study Alert! 🩺💔
Do beta-blockers still help after a heart attack if there's no heart failure? 🤔
In the BETAMI–DANBLOCK trial (🇩🇰+🇳🇴, n=5574), beta-blocker therapy in post-MI patients with preserved or mildly reduced LVEF (≥40%) modestly reduced the composite outcome of death or major cardiovascular events 🧠📉
📌 Primary endpoint: 14.2% (BB) vs. 16.3% (no BB) → HR 0.85, p=0.03
💡 Especially lowered risk of recurrent MI (HR 0.73)
🧠 Even in the era of PCI, DAPT & statins, beta-blockers may still bring benefit — especially in patients with mildly reduced LVEF (40–49%) 🫀
🔗 [Add your slide link or DOI here]
#Cardiology #NEJM #HeartAttack #BetaBlockers #PostMI #EvidenceBasedMedicine #LVEF #PrecisionMedicine #ClinicalTrials