💊Baxdrostat, Blood Pressure, Breakthrough! New Hope for Uncontrolled Hypertension
Dr RR Baliga's "Got Knowledge Doc" Podkast
Audio is streamed directly from the publisher (traffic.libsyn.com) as published in their RSS feed. Play Podcasts does not host this file. Rights-holders can request removal through the copyright & takedown page.
Show Notes
🚨 New NEJM Study Alert! 🧬💊
Baxdrostat, a selective aldosterone synthase inhibitor, shows significant BP reduction in patients with resistant & uncontrolled hypertension despite RAAS blockade and diuretic therapy.
✅ SBP ↓ ~9–10 mmHg at 12 weeks
🧂 Targets salt-retaining physiology
⚖️ Well-tolerated: early mild hyperkalemia & hyponatremia
🔁 Durable effect even after withdrawal
A promising step toward precision therapy in tough-to-treat hypertension!
📖 Read more: NEJM Aug 2025 | BaxHTN Trial
#Hypertension #Cardiology #Baxdrostat #Aldosterone #RAAS #NEJM #PrecisionMedicine #ClinicalTrials