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Basilar Artery Blockage. Bolus Breakthrough. Better Outcomes. 🧠💉📈

Basilar Artery Blockage. Bolus Breakthrough. Better Outcomes. 🧠💉📈

Dr RR Baliga's "Got Knowledge Doc" Podkast

February 25, 20266m 24s

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Show Notes

Can a single bolus change the fate of a devastating stroke? 🧠💉

The TRACE-5 trial (Lancet 2026) shows that tenecteplase within 24 h for basilar artery occlusion improves excellent functional outcomes (38% vs 29%; RR 1.50, p=0.014) without increased haemorrhage or mortality. 📊

Pragmatic design. No mandatory advanced imaging. Feasible globally. 🌍

If confirmed beyond Asian cohorts, this could reshape late-window stroke care.

Single shot. Shifted scale. Strong signal. 🚑📈