ATTR-CM Under Siege ⚔️ Vutrisiran's Defense 🛡️ Victory for the Heart 🏆
Dr RR Baliga's "Got Knowledge Doc" Podkast
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Show Notes
🚨 New Insights from HELIOS-B 🫀✨
In patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM), the RNA interference therapy vutrisiran not only reduced mortality and cardiovascular events, but also showed measurable benefits in cardiac structure and function over 30 months.
📉 Thinner LV walls & lower LV mass index
💪 Preserved ejection fraction & stroke volume
⚙️ Improved diastolic function – better E/e′ & e′ velocity
🏆 Benefits seen even with substantial tafamidis use
These findings support early initiation of vutrisiran to protect the heart and slow disease progression.
#Cardiology #HeartFailure #ATTRCM #RNAi #Vutrisiran #HELIOSB #Echocardiography #HeartHealth ❤️