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Reanalysis of Popular Antidepressant Trial Uncovers Reporting Flaws

Reanalysis of Popular Antidepressant Trial Uncovers Reporting Flaws

Dr. Joseph Mercola - Take Control of Your Health · Dr. Joseph Mercola

September 16, 20258m 14s

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Show Notes

  • A reanalysis of a study found that fluoxetine alone showed no measurable benefit over placebo in treating adolescent depression after 12 weeks
  • Researchers uncovered 11 additional suicide-related events that were hidden or misclassified, bringing the total to 21 serious incidents
  • Statistical tactics and selective reporting made fluoxetine appear safer and more effective than it really was in clinical trials
  • A different reanalysis mentioned that adverse events and many side effects were minimized or excluded from the original reports
  • Improving gut health, getting regular exercise, undergoing therapy, and optimizing vitamin D are viable approaches for treating depression