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Does Vit B6 Reduce Mastalgia? New Meta-analysis 09/2025

Does Vit B6 Reduce Mastalgia? New Meta-analysis 09/2025

Dr. Chapa's OBGYN No Spin Podcast · Hector Chapa

September 11, 202521m 43s

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Show Notes

Mastalgia is a common breast complaint in reproductive aged women. Mastalgia can be separated into three categories: 1) cyclical, 2) noncyclical, and 3) extramammary. Vitamin B6 is often cited as a homeopathic (non-prescription/pharmacological) remedy for simple mastalgia. Does the published data support its use? A newly published meta-analysis sheds light on the subject.

  1. Sharifipour, F., Siahkal, S.F. & Bagherinia, M. The effectiveness of vitamin B6 in reducing mastalgia: a systematic review and meta-analysis. BMC Women's Health 25, 421 (2025). https://doi.org/10.1186/s12905-025-03991-x
  2. ACOG PB 164; reaffirmed 2023