Rationale for NTRK Testing in Patients With Cancer
In this podcast episode, join George D. Demetri, MD, and Alexander Drilon, MD, to learn why, when, and how to test for NTRK fusions in patients with diverse solid tumors.
Decera Clinical Education Oncology Podcast · Alexander Drilon MD, George D. Demetri MD
Audio is streamed directly from the publisher (afp-928689-injected.calisto.simplecastaudio.com) as published in their RSS feed. Play Podcasts does not host this file. Rights-holders can request removal through the copyright & takedown page.
Show Notes
In this episode, George D. Demetri, MD, and Alexander Drilon, MD, discuss the biologic rationale behind testing for NTRK fusions in patients with various solid tumors, along with clinical strategies for testing. Topics include:
- Differences between NTRK fusions vs gene mutations
- Frequency of NTRK fusions by age and tumor type
- When to test patients for NTRK fusions and interpreting reports
- Methods of testing: multiplex gene testing, next-generation sequencing of DNA vs RNA, immunohistochemistry, and liquid biopsy
Presenters:
George D. Demetri, MD
Professor of Medicine
Harvard Medical School
Harvard University
Co-Director, Ludwig Center at Harvard
Senior Vice President for Experimental Therapeutics
Director, Sarcoma Center
Dana-Farber Cancer Institute
Boston, Massachusetts
Alexander Drilon, MD
Chief, Early Drug Development
Attending, Thoracic
Memorial Sloan Kettering Cancer Center
New York, New York
Link to full program:
https://bit.ly/2YFIPfr
Link to slideset based on this podcast:
https://bit.ly/3amgU6w
Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.