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Bladder Cancer Breakthroughs: New NMIBC Therapies and EV + Pembrolizumab Updates From ASCO GU 2026
Episode 238

Bladder Cancer Breakthroughs: New NMIBC Therapies and EV + Pembrolizumab Updates From ASCO GU 2026

In this episode, experts discuss the rapidly evolving bladder cancer treatment landscape, including new options for BCG-unresponsive disease, emerging perioperative regimens, and the growing role of biomarkers and multidisciplinary care in guiding treatment decisions.

Decera Clinical Education Oncology Podcast · Sam S. Chang MD MBA, Matthew D. Galsky MD

March 23, 202618m 57s

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Show Notes

In this episode, Sam S. Chang, MD, MBA, and Matthew D. Galsky, MD, discuss the rapidly evolving treatment landscape in bladder cancer, highlighting new therapeutic options, emerging clinical trial data, including the latest results presented at ASCO GU 2026, and the growing role of biomarkers and multidisciplinary care, including:

  • New treatment options for BCG-unresponsive non–muscle-invasive bladder cancer
  • Intravesical therapies such as nadofaragene and N-803
  • The role of ctDNA in measurable residual disease detection

Presenters:

Sam S. Chang, MD, MBA
Patricia and Rodes Hart Chair of Urologic Surgery
Chief Surgical Officer
Vanderbilt Ingram Cancer Center
Nashville, Tennessee

Matthew D. Galsky, MD
Lillian and Howard Stratton Professor of Medicine
Icahn School of Medicine at Mount Sinai
Director, Genitourinary Medical Oncology
Co-Leader, Cancer Clinical Investigation Program
Associate Director for Translational Research
Tisch Cancer Institute
New York, New York

Link to full program: 
https://bit.ly/479RgQn

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Topics

bcg tokyo-172bcg-unresponsive diseasectdnakeynote-b15ev-304evnon-muscle invasive bladder cancernmibcbladder cancerpembrolizumabnadofaragenekeynote-905swog s1602nadofaragene firadenovecbacillus calmette–guérinnon-muscle-invasive bladder cancerbcgmibcswog 1602mrdcirculating tumor dnanogapendekins1602minimal residual diseasemuscle-invasive bladder cancerenfortumab vedotintice bcgintravesical therapybcg-naive diseasen-803nogapendekin alfa inbakicept