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Setting Our Sights on Symptom Management: Raising the Bar in PBC Management Podcast
Episode 494

Setting Our Sights on Symptom Management: Raising the Bar in PBC Management Podcast

Historically, key symptoms of primary biliary cholangitis (PBC), such as pruritus and fatigue, have been understudied and undertreated. Listen now to learn from Dr Aliya F. Gulamhusein, Dr Christopher L. Bowlus, and Dr Aparna Goel, how symptom management should be considered independently of PBC management, and how new therapeutic agents can help. This episode is the third of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care.

Decera Clinical Education Infectious Disease Podcast · Aparna Goel MD, Christopher L. Bowlus MD, Aliya F. Gulamhusein MD MPH FRCPC

February 3, 202638m 4s

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Show Notes

Historically, key symptoms of primary biliary cholangitis (PBC), such as pruritus and fatigue, have been understudied and undertreated. Listen now to learn how symptom management should be considered independently of PBC management, and how new therapeutic agents can help.

Topics covered include:

  • Mechanisms of pruritus and fatigue in PBC
  • Nonpharmacologic treatment options
  • An overview of clinical trial data supporting second-line agents for symptom management:
  • Bezafibrate
  • Elafibranor
  • Seladelpar
  • Investigational agents:
  • Volixibat
  • Linerixibat
  • Setanaxib

This episode is the third of 3 recap podcasts, featuring audio from our live satellite symposium, Raising the Bar: Innovations in PBC Care. For the full on-demand webcast of this satellite symposium, and to download the accompanying slides, visit the program page for this episode:
https://bit.ly/44ZJ5os

Presenters:
Christopher L. Bowlus, MD
Lena Valente Professor and Chief
Division of Gastroenterology and Hepatology
School of Medicine
University of California Davis
Sacramento, California

Aparna Goel, MD
Clinical Associate Professor of Medicine
Division of Gastroenterology and Hepatology
Stanford University
Palo Alto, California

Aliya F. Gulamhusein, MD, 
MPH, FRCPC
Professorship in PSC Research
Clinician Investigator, Toronto General Hospital
Assistant Professor, University of Toronto
Division of Gastroenterology and Hepatology
University Health Network
Toronto, Canada

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Topics

cirrhosisocaobeticholic acidpparcholestatic itchprimary biliary cholangitisantimitochondrial antibodyseladelpar  elafibranorsetanaxibprurituslinerixibatbile acid-binding resinsfatiguepbcvolixibatppar agonistrifampinitchama