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Modernizing CMV Preventive Approaches
Episode 327

Modernizing CMV Preventive Approaches

Listen to Hannah Imlay, MD, MS, explore concepts in CMV prevention in solid organ transplantation, including comparison of prevention strategies, international guideline recommendations, monitoring strategies, and future prevention approaches.

Decera Clinical Education Infectious Disease Podcast · Hannah Imlay MD MS

November 6, 202318m 12s

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Show Notes

In this episode, Hannah Imlay, MD, MS, discusses cytomegalovirus (CMV) prevention strategies in solid organ transplantation (SOT) recipients including:

  • Strategies for preventing CMV in SOT
  • International guideline recommendations for CMV prevention strategies by organ type
  • Antivirals used for CMV prevention
  • Comparison of preemptive therapy vs prophylaxis for CMV prevention in liver transplant recipients
  • Comparison of letermovir vs valganciclovir for CMV prophylaxis in kidney transplant recipients
  • Use of CMV cell–mediated immunity monitoring for primary prophylaxis
  • Monitoring CMV viral loads, including limitations to quantitative nucleic acid testing
  • Future prevention approaches

Faculty:

Hannah Imlay, MD, MS
Assistant Professor of Medicine
Department of Internal Medicine, Division of Infectious Diseases
University of Utah  
Salt Lake City, Utah

Content based on a CME program supported by an educational grant from Merck & Co., Inc., Rahway, NJ, USA.

Follow along with a downloadable slideset at: 
https://bit.ly/476v2wI

Link to full program: 
https://bit.ly/47lNK2K


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Topics

antiviralsqnatresistance-associated substitutionsletermovirpreemptive therapyprophylaxispreventionlate onset diseaseimmune monitoringliverhybridviral loadcmvkidneycmv-specific neutralizing antibodiesvaccinesvalganciclovircmv diseasehannah imlaycmv cell-mediated immunityimmune responsessolid organ transplantationindirect effectsdnaemiarisk stratificationdrug toxicitycmv infectionserologic statusquantitative nucleic acid testinginternational guidelines