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Challenging Scenarios: Managing Virologic Failure in a Heavily Treatment–Experienced Patient
Episode 304

Challenging Scenarios: Managing Virologic Failure in a Heavily Treatment–Experienced Patient

Listen as an expert uses a case scenario to discuss choosing a new ART regimen for a person living with HIV who is heavily treatment experienced with multidrug-resistant HIV, including guideline recommendations and data for novel-mechanism ART agents.

Decera Clinical Education Infectious Disease Podcast · Renslow Sherer MD

August 22, 202319m 32s

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Show Notes

In this episode, Renslow Sherer, MD, discusses managing virologic failure in a person living with HIV who is heavily treatment experienced, including:

  • Guideline recommendations for selecting a new ART regimen
  • Options for patients with multidrug-resistant HIV from existing drug classes and novel mechanisms of action with no cross-resistance
  • Data from TMB-301 and TMB-311 for ibalizumab, BRIGHTE for fostemsavir, and CAPELLA for lenacapavir on the use of these agents for people living with HIV who are heavily treatment experienced with multidrug-resistant HIV

Presenter:

Renslow Sherer, MD
Director
International HIV Training Center
Professor of Medicine
Section of Infectious Diseases and Global Health
Department of Medicine
University of Chicago
Chicago, Illinois

To download the slides:
https://bit.ly/3OcqxIE

To view the full online program:
https://bit.ly/3ZjSFhg


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Topics

treatment experienceddolutegravirnucleoside reverse transcriptase inhibitoribalizumabintegrase inhibitorpiheavily treatment experienceddtgart failurenovel mechanismsalvage regimenbrightelenacapavirantiretroviral therapydarunavirdrvearnestgenotypingnadiaibatmb-311salvage therapytmb-301/-311mdrinstiresistancetmb-301ftrproviral dnamultidrug resistantnrticapellalenrecycling nrtisartprotease inhibitorhtefostemsavirhiv