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Addressing Age-Related Comorbidities Among People With HIV
Episode 3

Addressing Age-Related Comorbidities Among People With HIV

Hear insights from Dr. Daniel Kuritzkes and Dr. Christian Ramers on preventing ART-associated bone loss, reducing cardiovascular disease risk, and managing HIV-associated neurocognitive disorders in this case-based discussion of comorbidity management and ART selection for aging patients with HIV.

Decera Clinical Education Infectious Disease Podcast · Daniel R. Kuritzkes MD, Christian B. Ramers MD MPH

June 5, 202029m 36s

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Show Notes

In this episode, Dr. Kuritzkes and Dr. Ramers provide a case-based discussion addressing several age-related comorbidities among people with HIV, including bone loss, renal impairment, cardiovascular disease, mental health disorders, and neurocognitive disorders. Their discussion includes analysis of key data from the following HIV studies: 

  • DRIVE-AHEAD: Neuropsychiatric Events With First-line DOR/3TC/TDF vs EFV/FTC/TDF
  • TANGO: Renal and Bone Changes With Switch to DTG/3TC
  • SWORD-1/2: Renal and Bone Changes With Switch to DTG + RPV
  • Study 1961: Quantitative Proteinuria by Baseline Regimen With Switch to BIC/FTC/TAF in Women
  • Studies 1216 and 1160: Bone Changes With Switch to RPV/FTC/TAF
  • NA-ACCORD: Increased MI Risk Among PWH
  • D:A:D: Increased CVD Risk With Boosted PIs
  • Danish HIV Cohort Study: Impact of Smoking on MI Risk
  • D:A:D: Impact of Smoking on MI Risk

In addition, Dr. Kuritzkes and Dr. Ramers discuss relevant data and practical strategies for smoking cessation among people with HIV as well as risk factors, pathogenesis, and challenges in the clinical management of HIV-associated neurocognitive disorders.

Presenters:

Daniel R. Kuritzkes, MD
Chief, Division of Infectious Diseases
Brigham and Women’s Hospital
Harriet Ryan Albee Professor of Medicine
Harvard Medical School
Boston, Massachusetts

Christian B. Ramers, MD, MPH
Associate Clinical Professor
Division of Infectious Diseases
Department of Medicine
UC San Diego School of Medicine
La Jolla, California
Chief, Population Health
Director, Graduate Medical Education
Family Health Centers of San Diego
San Diego, California

Content based on an online CME program supported by an independent educational grant from ViiV Healthcare.

Link to downloadable slideset associated with this podcast:  https://bit.ly/2MuoEHF

Link to full program: 
https://bit.ly/3cFzy8o


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Topics

hiv smokingdoravirinehiv drive-aheadna-accordhiv handhiv neurocognitivehiv proteinuriaefv/ftc/tdfdolutegravir/lamivudinehiv renal functionhiv swordhiv hadhiv switchbic/ftc/tafhiv-associated dementiahiv mental healthhiv-associated neurocognitive disordersbictegravirantiretroviral therapyhiv cvdrpv/ftc/tafhiv cardiovascular diseasehiv mihiv myocardial infarctionhiv womenhiv neuropsychiatricefavirenzhiv tangohiv agingdor/3tc/tdfhiv older patientshiv smoking cessationhiv treatmentd:a:dhiv bone lossdtg/3tchiv first-linearthiv bmdboosted pis cvd riskhivhiv 2-drug regimens