DDx
74 episodes — Page 2 of 2
Classic Symptoms of Rare Diseases and Avoiding Diagnostic Odysseys
Rare diseases are … rare … which makes even textbook cases difficult to diagnose. In this episode, we’ll talk about the…
DDx Returns for Season Five
Rare diseases are … rare … which makes even textbook cases difficult to diagnose. In this season, we’ll talk about the…
ALS, DMD and Adapting Treatment Mechanisms for Genetic Variations
In this episode, we’ll dig into the different mechanisms by which gene therapy can potentially treat specific genetic…
Gene Therapy in Action: Adeno-Associated Viral Vectors
Adeno-associated viral vectors, or AAVs, are the tiny shells of viruses. And today they are the most common vessels for…
The Future of Gene Therapy and Genetic Diseases
Peek into the future of gene therapy and its capacity to treat – maybe eliminate – genetic diseases like cancers and…
How Does Gene Therapy Work? Correcting Disease-Causing Genetic Variations
Not all genetic variations are associated with threats or harms to human health. Some even protect us, such as genetic…
A Brief History of Gene Therapy and the Discovery of DNA
In this episode, we explore some of the major scientific findings – like discovering DNA – that set the stage for the…
DDx is Back for Season Four
Take a deep dive into one of the most awe-inspiring medical innovations of our time: gene therapy. It’s comparable to some…
Searching for zebras
Few patients. A scarcity of literature. Working in rare disease can feel like you’re standing at the edge of an abyss with…
Hunting for a diagnosis
After a patient in his early 30s develops muscle weakness so severe he requires a wheelchair, he’s diagnosed with multiple…
When the fever breaks
A one-year old boy is brought to his doctor with a history of febrile seizures, odd movements, and developmental delay. His…
Code blue
“Code blue, unit 305. Code blue, unit 305.” After an 8-year-old boy with recurrent episodes of rhabdomyolysis is…
DDx Returns for a Third Season
Welcome back to DDx, a show about how doctors think. In Season 3, focused on rare disease, you’ll meet the doctors…
Psoriasis and Mental Health (Sponsored)
A common skin condition affects much more than a patient’s skin, and misinformation only exacerbates the stigma. This…
Pattern Recognition Can Save a Life
A dermatologist is paged to examine a rare condition. But something doesn’t add up. Head to Figure1.com/ddx, where you can…
Rash Decision
What do you do when faced with a set of symptoms that has two contradictory courses of treatment? Head to Figure1.com/ddx,…
Why Skin Color Matters
Unconscious bias can run so deep that patients and doctors alike can miss a potentially fatal diagnosis. Head to…
Scratching the Surface (Sponsored)
A patient presents with fever, swollen digits, and skin “the color of a red delicious apple.” She’s been scratching so hard…
Sudoku seizures.
A young man’s near-death experience results in a very puzzling diagnosis on the season finale of DDx.
Extreme reactions to marijuana.
Chronic vomiting, a flushed complexion, and acute agitation: can cannabis be the cause? A growing consensus among doctors…
Young, fit and female? Higher chance of misdiagnosis.
Welcome to DDx, an original podcast by Figure 1 about how doctors think. On episode 1, host and emergency doctor Raj…
The near-miss.
A patient says she feels fine. A quick-thinking doctor arrives at a dire and uncommon diagnosis. Then it happens again. And…
The source of the bleed.
A patient with an acute subdural hematoma presents with no sign of head trauma. The search for an answer almost overlooks an…
Anchoring bias and the frequent flyer.
A 19-year-old with sickle cell disease is well-known to ER doctors as a “frequent flyer”. Every time they see her it’s due to…