Coronavirus (COVID-19) Q&A

Ford Foundation President Darren Walker discusses the role of philanthropic organizations in responding to the COVID-19 pandemic and to health inequities. Recorded July 28, 2020. Related Article(s): The Work of Philanthropy in Responding to COVID-19 and Addressing Inequality

David N. Fisman, MD, MPH joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study that examines the trends and risk factors associated with coronavirus disease 2019 (COVID-19) death in long-term care facilities in Ontario, Canada. Read the article here: https://ja.ma/39oLDyy. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Eric Topol, MD, Scripps Research EVP and omnivorous science health care and tech commentator, discusses the evolving COVID-19 pandemic. Recorded July 23, 2020. Related Article: Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers

Catherine L. Auriemma, MD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study that examines changes in completion of and expressed preferences on an online advanced directive platform during the coronavirus 2019 (COVID-19) pandemic. Read the article here: https://ja.ma/39gbXLe. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Both remdesivir and dexamethasone have been promoted as effective treatments for COVID-19. JAMA Deputy Editor Greg Curfman, MD, and Professor Rachel Sachs, JD, from the Washington University School of Law discuss the science and health policy aspects of these COVID-19 treatments. Related Article(s): Missed Opportunities on Emergency Remdesivir Use

CDC Director Robert R. Redfield, MD, discusses the ongoing COVID-19 pandemic and the agency's latest recommendations. Recorded July 14, 2020. Related Article(s): Universal Masking to Prevent SARS-CoV-2 Transmission—The Time Is Now

Kalpalatha K. Guntupalli, MD, of Baylor College of Medicine discusses the surge and ICU management of COVID-19 patients in Houston, Texas. Recorded July 10, 2020. Related Article(s): Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

Ramez Kouzy, MD, Joseph Abi Jaoude, MD, and Ethan Ludmir, MD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a systematic review examining current randomized clinical trials of therapeutic agents to treat coronavirus disease 2019 (COVID-19). Read the article here: https://ja.ma/2B21PJs.

Whether the SARS-CoV-2 virus is transmitted by droplets or aerosol influences which public health interventions might slow its spread. Michael Klompas, MD, professor of medicine at Harvard Medical School, explains evidence to date about mechanisms of coronavirus transmission and implications for pandemic containment and mitigation efforts. Related: Airborne Transmission of SARS-CoV-2: Theoretical Considerations and Available Evidence

Infectious disease physician Rochelle P. Walensky, MD, of Harvard University discusses the ongoing COVID-19 pandemic. Recorded July 8, 2020. Related Article: Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection

Anthony Fauci, MD, White House Coronavirus Task Force member and Director of the National Institutes of Allergy and Infectious Diseases, discusses latest developments in the COVID-19 pandemic. Recorded on July 2, 2020.

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses latest developments in the COVID-19 pandemic. Recorded on June 29, 2020. Related Article(s): Interpreting Diagnostic Tests for SARS-CoV-2

Interview with Daniel M. Weinberger, PhD, author of Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020

Intensivists Flavia R. Machado, MD, PhD, of the Federal University of São Paulo, and Jorge Salluh, MD, PhD, of the D'OR Institute for Research and Education in Rio de Janeiro, discuss the surge of COVID-19 cases and ICU management of patients in Brazil. Recorded June 26, 2020. Related Article(s): Latin America and Its Global Partners Toil to Procure Medical Supplies as COVID-19 Pushes the Region to Its Limit

Alhaji Cherif, PhD and Peter Kotanko, MD join JAMA Network Open Editors to discuss a study examining the feasibility of using pool testing to identify patients with coronavirus disease 2019 (COVID-19) in a setting with limited testing availability. Read the article here: https://ja.ma/3e8OCvJ JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Chicago public health legend and retired physician Linda Rae Murray, MD, discusses systemic racism and the pandemic's disproportionate effect among African Americans and other people of color with JAMA Medical News Associate Managing Editor Jennifer Abbasi. Dr Murray is an adjunct assistant professor at the University of Illinois at Chicago School of Public Health and a past president of the American Public Health Association. Related: Taking a Closer Look at COVID-19, Health Inequities, and Racism

Michael Osterholm, PhD, MPH, of UMN's Center for Infectious Disease Research and Policy, discusses the summer rise in US COVID-19 cases, prospects for school reopening, a "second wave" in the fall, and more. Recorded June 24, 2020. Related Article(s): Vulnerability to Pandemic Flu Could Be Greater Today Than a Century Ago

Gina M. Piscitello, MD joins JAMA Network Open Editors to discuss a systematic review that examines US state guidelines for ventilator allocation decision-making during the coronavirus disease 2019 pandemic. Read the article here: https://ja.ma/2YpfVxf. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Fabio Ferreli, MD, and Giuseppe Mercante, MD, authors of Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019

Infectious disease and global health expert Carlos del Rio, MD, of Emory University provides an update on the status of the #COVID19 pandemic in summer 2020, prospects for effective treatment and prevention, communicating the ongoing risk to the public, and more. Recorded June 15, 2020. Related Article: Translating Science on COVID-19 to Improve Clinical Care and Support the Public Health Response

COVID-19 critical care update with Maurizio Cecconi, MD, of Humanitas University in Milan, Italy, and JAMA Associate Editor Derek C. Angus, MD, MPH, of the University of Pittsburgh. Recorded June 8, 2020. Related Article: Management of COVID-19 Respiratory Distress

Joseph M. Unger, PhD joins JAMA Network Open Editors to discuss a cohort study investigating how the coronavirus disease 2019 (COVID-19) pandemic is associated with national enrollment in cancer clinical trials. Read the article here: https://ja.ma/2MNv1Gs. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Jay Shore, MD, MPH, author of Telepsychiatry and the Coronavirus Disease 2019 Pandemic—Current and Future Outcomes of the Rapid Virtualization of Psychiatric Care

Joshua M. Sharfstein, MD, and Christopher Morphew, PhD, of Johns Hopkins University discuss options for opening primary, middle, and high schools in fall 2020. Recorded June 3, 2020. Related Article: The Urgency and Challenge of Opening K-12 Schools in the Fall of 2020

NIAID Director Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor in Chief Howard Bauchner, MD. Recorded June 2, 2020. Related Article(s): Anthony Fauci, MD, on COVID-19 Vaccines, Larry Kramer, and Dealing With Criticism

Paul Offit, MD, of the Children's Hospital of Philadelphia, discusses principles and progress to date in COVID-19 vaccine development. Recorded June 1, 2020. Related: Interview with Brit Trogen, MD, MS, author of Adverse Consequences of Rushing a SARS-CoV-2 Vaccine: Implications for Public Trust

Tristan Morichau-Beauchant, MD joins JAMA Network Open Editors to discuss a case series that reports a systematic assessment of deep vein thrombosis among patients in an intensive care unit in France with severe coronavirus disease 2019 (COVID-19). Read the article here: https://ja.ma/307784k. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Paul Starr, PhD, Professor of Sociology and Public Affairs at Princeton University, discusses policy options for achieving a new normal in the COVID-19 pandemic. Recorded Thursday, May 28, 2020. Related Article: Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic

US National Institutes of Health (NIH) Director Francis S. Collins, MD, PhD, discusses the agency's new initiative to collaborate with other agencies and industry to accelerate development and testing of COVID-19 treatments and vaccines. Recorded May 19, 2020. Related: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): An Unprecedented Partnership for Unprecedented Times

The University of New Mexico's Eileen Barrett, MD, MPH, speaks with JAMA's Jennifer Abbasi about the pandemic's mental and emotional toll on health care workers—and how they and their employers can safeguard their well-being. Read the article: Prioritizing Physician Mental Health as COVID-19 Marches On

Was the stay-at-home order in Illinois associated with different rates of coronavirus disease 2019 (COVID-19) compared with Iowa, which did not issue a stay-at-home order? Wei Lyu, MS and George L. Wehby, PhD join JAMA Network Open Editors to discuss a cross-sectional study comparing coronavirus disease 2019 (COVID-19) cases in border counties in Iowa and Illinois to find out if issuing a stay-at-home order helped limit the spread of COVID-19 cases. Read the article here: https://ja.ma/2LNprmO. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Ezekiel Emanuel, MD, PhD, of the Perelman School of Medicine's Department of Medical Ethics and Health Policy, discusses the use of immunity licensing (immunity passports) as a means to restore public travel, activity, and the economy following the first wave of the COVID-19 pandemic. Recorded May 11, 2020. Related: The Ethics of COVID-19 Immunity-Based Licenses ("Immunity Passports")

Ruoran Li, MPhil joins JAMA Network editors to discuss a comparative effectiveness study describing and comparing the intensive care unit and inpatient bed needs for patients with coronavirus disease 2019 (COVID-19) in 2 cities in China to estimate the peak number of intensive care unit beds needed in US cities if an outbreak equivalent to that in Wuhan occurs. Read the article here: https://ja.ma/3cySE0m. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Preprint servers and professional discourse on social media sites like Twitter have been incredibly helpful in spreading useful information as the COVID-19 pandemic changes over time. But they clearly function as a double-edged sword, spreading information rapidly prior to traditional peer review. JAMA Network Open Editors Eli Perencevich, MD, MS and Roy Perlis, MD, MSc join us to discuss on JNOLive. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Don Berwick, MD, MPP, of the Institute for Healthcare Improvement, discusses choices societies and the medical profession can make to improve health care and reduce inequities as we move out of the acute phase of the coronavirus pandemic.

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses evolution of CDC guidance and latest developments in the COVID-19 pandemic. Recorded Friday May 1, 2020.

Interview with Hsien-Ho Lin, MD, ScD, author of Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan and Risk at Different Exposure Periods Before and After Symptom Onset

The US spends more on health care as a proportion of its GDP than any other nation. Will the COVID-19 pandemic reduce or accelerate that spending? Sherry Glied, PhD, Dean and Professor of Public Service at New York University, explains. Recorded Monday, April 27, 2020. Read the article The Potential Effects of Coronavirus on National Health Expenditures

Steven M. Bradley, MD, MPH joins JAMA Network editors to discuss a randomized clinical trial evaluating the safety and efficacy of 2 chloroquine diphosphate dosages in patients with severe coronavirus disease 2019 (COVID-19). Read the editorial here: https://ja.ma/2JC5sGx. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

A new exhibit on the 1918 flu pandemic asks: What is an individual's responsibility to their community during a pandemic? Exhibit curator Jane Boyd and museum manager Nancy Hill take Jennifer Abbasi on a tour of the medical museum's new exhibit just weeks before the COVID-19 outbreak first emerged. Pandemic Part 1: 1918 Flu Pandemic and COVID-19 Read the article: Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Medical historian Howard Markel, MD, PhD, director of the University of Michigan's Center for the History of Medicine, speaks with JAMA Fishbein fellow Angel Desai, MD, about lessons from the devastating 1918 flu pandemic. Markel discusses his research into the effects of social distancing on US death rates during the worldwide outbreak. Pandemic Part 2: A Trip to Philadelphia's Mutter Museum Read the article: Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Marc Lipsitch, DPhil, an infectious diseases epidemiologist developing biological and modeling approaches to pathogen transmission and outbreaks, discusses evolution of the COVID-19 pandemic in summer and fall 2020. Originally recorded April 22, 2020.

Management of COVID-19-related respiratory failure differs from what is necessary for ARDS. Rather than having alveolar edema, COVID-19 patients have pulmonary vascular dysregulation. Gas exchange is severely compromised with little reduction in lung compliance. Ventilatory support for COVID-19 patients requires higher than normal tidal volumes with minimal PEEP and allowance for higher than usual serum CO2 levels. How the unique pathophysiology of respiratory failure should be treated is discussed by John J. Marini, MD, professor of medicine at the University of Minnesota.

JAMA Health Forum editors John Ayanian, MD, MPP, and Melinda Buntin, PhD, discuss changes in US health care and health policy driven by the coronavirus pandemic. Recorded April 16, 2020.

Rochelle Walensky, MD, MPH, of Harvard University discusses public health strategies and policies for lifting shelter-in-place and quarantine and for returning the US to a new post-first-wave normal. Recorded Monday April 20, 2020.

New York City coronavirus update from Mitchell Katz, MD, President and CEO of NYC Health + Hospitals, the largest municipal public health system in the United States. Recorded April 13, 2020.

Questions about testing, chloroquine toxicity, duration of immunity and reinfection, and what to expect next are gripping the US as the novel coronavirus spreads. JAMA Associate Editor Preeti Malani, MD, professor of medicine and Chief Health Officer at the University of Michigan, discusses recent developments in a live conversation with JAMA Editor in Chief Howard Bauchner. Recorded on April 6, 2020.

NIAID Director and Presidential Coronavirus Task Force Advisor Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor Howard Bauchner, MD. Recorded April 8, 2020.

US states are taking the lead in managing the COVID-19 pandemic. What can state governors expect from the federal government and from the US Department of Health and Human Services? Governor Mike Leavitt from Leavitt Partners joins JAMA Editor Howard Bauchner, MD, in this live Q&A. Recorded April 8, 2020.

Shortages of face masks and N95 respirators have forced clinicians and hospitals to reuse these normally disposable items. Ron Shaffer, PhD, former CDC PPE Research Branch Chief, discusses effective sterilization techniques and how to test that the equipment stays protective after sterilization.