BMJ talk medicine
500 episodes — Page 9 of 10

The PARCER Trial with Supriya Chopra
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Dr. Supriya Chopra. Dr. Chopra is a Professor in Radiation Oncology at ACTREC, Tata Memorial Centre and Principal Investigator of the PARCER trial. Her research focus is to improve outcomes of cervical cancer through use of advanced radiation techniques in patients undergoing RT for both primary and recurrent metastatic cervical cancer. She also co-leads multi-institutional molecular translational research programme (BIOEMBRACE) for cervix cancer. HIGHLIGHTS: - Postoperative Adjuvant Radiation in Cervical Cancer (PARCER), a phase III randomized trial, compared late toxicity after image-guided intensity-modulated radiotherapy (IG-IMRT) with three-dimensional conformal radiation therapy (3D-CRT) in women with cervical cancer undergoing postoperative radiation. - IG-IMRT results in reduced toxicity with no difference in disease outcomes in cervical cancer. - The 3-year cumulative incidence of grade ≥ 2 late GI toxicity in the IG-IMRT and 3D-CRT arms were 21.1% versus 42.4%. - The cumulative incidence of grade ≥ 2 any late toxicity was 28.1% versus 48.9%. - Patients reported reduced diarrhea (P = .04), improved appetite (P = .008), and lesser bowel symptoms (P = .002) with IG-IMRT. - The 3-year pelvic relapse-free survival and disease-free survival in the IG-IMRT versus the 3D-CRT arm were 81.8% versus 84% and 76.9% versus 81.2%, respectively.

Quality improvement and wellbeing are inextricably linked
Over the course of the last few years, the BMJ has published a series of articles in our Quality Improvement series - aiming to give those new to improvement science a good grasp of how to think about changing things in healthcare. Then covid-19 came along, and it seemed like all of healthcare was now aimed at just surviving in the face of the pandemic, and all thoughts of quality improvement projects went out the window... But did they? Cat Chatfield, is joined by Will Warburton, former director of quality improvement at the Health Foundation, and advisor on the series. To read all of the open access articles mentioned in the discussion, visit https://www.bmj.com/quality-improvement

The role of medical students in activism
As medical students progress through medical school, some students are becoming dissatisfied by the lack of attention to socially relevant healthcare issues in the conventional curriculum, and begin to understand that some of the frustrations we encounter at work arise from political decisions. These issues have prompted medical students to voice their concerns and advocate for change. In this episode, we will be talking about activism, how to get involved and what you can do to push for change. Topics: • What makes an activist? • There is a role for everyone in activism • Things to bear in mind when considering civil disobedience Expert guest: Dr Rita Issa (@DrRitaIssa on Twitter) is a GP, public health academic, and activist. The groups that she’s helped (co)founded or worked with include Doctors for Extinction Rebellion, Docs Not Cops and Medact. Shout out to the following student-activists: Mikaela Loach (@mikaelaloach on Twitter) Rhiannon Osborne (@rhiannon_osborn on Twitter) Amit Singh (@amit_ankhi on Twitter) Marina Politis (@marinadpol on Twitter) Interested in getting involved? Here are some organisations that you can check out: Health for Green New Deal - https://www.medact.org/project/health-for-a-green-new-deal/ Student for Global Health - https://studentsforglobalhealth.org/ Doctors for Extinction Rebellion - https://www.doctorsforxr.com/ Docs not Cops http://www.docsnotcops.co.uk/ Check us out on social media: Twitter: https://twitter.com/BMJStudent Instagram: https://www.instagram.com/bmj_student/ Facebook: https://www.facebook.com/BMJStudent/ This podcast is produced and edited by Dom Byrne and Duncan Jarvies.

Elite athletes and pregnancy - the latest evidence and guidance with Dr Margie Davenport Ep #503
On this week’s BJSM podcast, we are joined by Assistant Professor Margie Davenport, to talk about the latest evidence and experience around exercising and competing as an elite athlete whilst pregnant. We discuss why this is such an important issue as well as some of the myths or misconceptions that exist in this space. Dr Davenport also provides a range of practical tips for team physicians, scientists and therapists to consider when it comes to advising athletes on planning pregnancies, training whilst pregnant, and shaping support networks and systems to support athletes that want to start a family? Here is the key paper and some other notable resources discussed in the podcast: Pushing for change: a qualitative study of the experiences of elite athletes during pregnancy https://bjsm.bmj.com/content/56/8/452 Why can’t I exercise during pregnancy? Time to revisit medical ‘absolute’ and ‘relative’ contraindications: systematic review of evidence of harm and a call to action https://bjsm.bmj.com/content/54/23/1395 Get Active Questionnaire for pregnancy checklist https://csep.ca/2021/05/27/get-active-questionnaire-for-pregnancy/

Sex differences in endovascular thrombectomy outcomes in large vessel occlusion
Sex disparities in acute ischemic stroke outcomes are well reported with IV thrombolysis. Despite several studies, there is still a lack of consensus on whether endovascular thrombectomy (EVT) outcomes differ between men and women. In this podcast, we discuss the Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT) study, in which women had similar discharge outcomes as men following EVT, in a propensity-matched cohort, but the improvement from discharge to 90 days was significantly worse in women, suggesting the influence of post-discharge factors. JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Johanna Fifi (Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York) and Amrou Sarraj (Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, Ohio). Paper available online: https://jnis.bmj.com/content/early/2022/02/28/neurintsurg-2021-018348. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767. Thank you for listening!

Updates and New Options in Advanced Ovarian Cancer
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Dr. Katherine Kurnit. Dr. Kurnit is an Assistant Professor at the University of Chicago in the section of Gynecologic Oncology. Her research interests include developmental therapeutics and early phase clinical trials for patients with gynecologic cancers. Highlights: Although surgical practices have changed over time, there is still much debate and no consistent consensus about timing or the use of new therapies such as HIPEC. More options for upfront maintenance therapy are now available for ovarian cancer patients. We need new treatment approaches for patients with platinum-resistant ovarian cancer. Finding ways to ensure ovarian cancer care is safe, feasible, and cost-effective in many different settings (nationally and internationally) will be important. New strategies for screening and prevention are sorely needed

Long Covid: what we know so far, with Dr Elaine Maxwell
In the first of a series of three episodes about Long Covid, Dr Roberta Heale, Associate Editor of Evidence-Based Nursing, speaks to Dr Elaine Maxwell, Nurse and author of two National Institute for Health Research reviews on evidence on Long Covid. They discuss the variance in reported Long Covid statistics, the impact of vaccinations, symptoms, and research efforts. The EBN podcast series on Long Covid is produced by Letícia Amorim and edited by Brian O'Toole. Please subscribe to the Evidence-Based Nursing podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Evidence-Based Nursing podcast iTunes page (https://podcasts.apple.com/gb/podcast/ebn-podcast/id942927408). Thank you for listening. To read more about this subject, follow the links: https://evidence.nihr.ac.uk/themedreview/living-with-covid19/ https://evidence.nihr.ac.uk/themedreview/living-with-covid19-second-review/

Challenges of Exercise and Physical Activity in Minorities with Dr. Meredith Turner. Ep #502
On this episode of the AMSSM (T: @TheAMSSM) Sports Medcast, host Dr. Jacob Wessels, MD, is joined by Dr. Meredith Turner, MD, who is one of the speakers in the Race and Sport session during the 2022 AMSSM Annual Meeting. In this conversation, Dr. Turner discusses her upcoming presentation in Austin, TX, on the Challenges of Exercise and Physical Activity in Minorities and address the following topics: · The definition of minority populations and how she first got interested in this topic · Identifying some of the primary barriers that minorities encounter regarding physical activity in their communities · How socioeconomic barriers that contribute to these health disparities in minorities · Ways that sports medicine professionals and healthcare providers can help recognize and address these factors in their communities Resources: Oliver, E. J., Dodd-Reynolds, C., Kasim, A., & Vallis, D. (2021). Inequalities and Inclusion in Exercise Referral Schemes: A Mixed-Method Multi-Scheme Analysis. International journal of environmental research and public health, 18(6), 3033. https://doi.org/10.3390/ijerph18063033 https://pubmed.ncbi.nlm.nih.gov/33809451/ Hawes, A. M., Smith, G. S., McGinty, E., Bell, C., Bower, K., LaVeist, T. A., Gaskin, D. J., & Thorpe, R. J., Jr (2019). Disentangling Race, Poverty, and Place in Disparities in Physical Activity. International journal of environmental research and public health, 16(7), 1193. https://doi.org/10.3390/ijerph16071193 https://pubmed.ncbi.nlm.nih.gov/30987098/ Physical activity deserts: What they are and how to reduce them with Dr. NiCole Keith. Ep #468 https://soundcloud.com/bmjpodcasts/physical-activity-deserts-what-they-are-and-how-to-reduce-them-with-dr-nicole-keith-ep-468

From Canada to Sweden. Effective roadside barriers, plus electric cars: opportunities vs safety cost
"Someone has to make a bold experiment once in a while". This month, we talk to Professor Robert Thomson, Mechanics and Maritime Sciences, Chalmers University of Technology, Gothenburg, Sweden. The discussion begins with PhD work on roadside barriers and ends with a discussion about commitment to grand visions, preventing injuries and saving lives. "Here's what you can do if your government and your society gets on board". The conversation, lead by Editor-in-Chief of Injury Prevention Rod McClure, also covers the unintended safety costs of electrification of modern vehicles. There remains a world of opportunity for the safety engineer. Please subscribe to the Injury Prevention Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify. If you enjoy our podcast, please consider leaving us a review and a 5-star rating on the Injury Prevention Podcast iTunes page (https://podcasts.apple.com/gb/podcast/injury-prevention-podcast/id942473946). Thank you for listening!

Mycoplasma Genitalium: Easy to detect, hard to treat
In this podcast, we focus on the bacterial genitourinary pathogen Mycoplasma genitalium (MGEN). We have known this pathogen for a long-time but only in recent years we have been testing and treating more frequently for this bacteria. In this conversation with Dr Fabiola Martin, STI's Podcast editor, Dr Emma Sweeney, Prof Catriona Bradshaw and Prof Nicola Low provide a clinical and research update on MGEN. Dr Emma Sweeney is a Postdoctoral researcher, The University of Queensland Centre for Clinical Research, Brisbane, Australia. Prof Catriona Bradshaw is a Clinician researcher based at Melbourne Sexual Health Centre, Melbourne, Australia. Prof Nicola Low is an Infectious disease epidemiologist, leading the Sexual and Reproductive Health Research Group at the Institute of Social and Preventive Medicine, University of Bern, Switzerland. Read the blog post: https://blogs.bmj.com/sti/2022/04/06/mgen/ Some relevant papers published by STI: Adverse pregnancy and perinatal outcomes, 2022, Frenzer C, Egli-Gany D, Vallely L, et al. https://sti.bmj.com/content/early/2022/03/28/sextrans-2021-055352 Prevalence in different populations, 2018, Baumann L, Cina M, Egli-Gany D, et al. https://sti.bmj.com/content/94/4/255 Persistence, concordance, complications in non-pregnant people, 2019, Cina M, Baumann L, Egli-Gany D, et al. https://sti.bmj.com/content/95/5/328

Challenging but achievable: reaching Low Lupus Disease Activity State (LLDAS) in childhood-onset SLE
Duane Peters from the Lupus Foundation of America talks to Dr Sylvia Kamphuis and Dr Javad Wahadat from the Erasmus Medical Center in Rotterdam in the Netherlands about aiming for a Low Lupus Disease Activity State (LLDAS) in children with systemic lupus erythematosus (SLE). They outline the difference between LLDAS and clinical remission (CR), and discuss how LLDAS may be a more achievable target for patients than CR that nevertheless still brings significant clinical benefits in terms of decreasing damage accrual and improving health-related quality of life. Access the paper here: https://lupus.bmj.com/content/8/1/e000571

Doctor Informed - Medicine's me too moments
In this episode we’re going to be talking about misogyny in surgery, recent revelations about sexual harassment in the theatre have emerged - but these behaviours have been endemic for a while, even as the profession seemed to ignore them. Joining Clara Munro is Baroness Helena Kenned, the author of a recent report into diversity in medicine, who, as a barrister, has long worked on discrimination cases. The reports mentioned in the episode are from the Royal College of Surgeons; https://www.rcseng.ac.uk/about-the-rcs/about-our-mission/diversity-review-2021/

ERAS and MIS for Same-Day Discharge
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Dr. Genevieve Bouchard-Fortier. Dr. Bouchard-Fortier is an assistant professor in the Division of Gynecologic Oncology in the Department of Obstetrics and Gynecology at the University of Toronto and a member of the Division of Gynecologic Oncology at the University Health Network/Sinai Health Systems. Her research is focused on improving the quality of care of gynecologic oncology patients as well as developing quality metrics to measure outcomes. Highlights: • We implemented a perioperative program to increase same day discharge rate after minimally invasive hysterectomy from 30% to 75% in gynecologic oncology patients. • ERAS principles significantly improved the same day discharge rate while maintaining a low complication rate. • Longer surgery, timing of surgery, and narcotic use were significantly associated with overnight admission.

Archimedes April 2022: Quality babies
Croaking and wheezing and slightly exhausted… not the average neonatologist but Archimedes this month is brought to you from post-natal palaces and 'post-nasal drip'. We start thinking about how best to communicate a post-natal diagnosis of Down syndrome(https://adc.bmj.com/content/107/4/409.1), which is prefaced by some thoughts on what it means to undertake a ‘good’ qualitative study(https://adc.bmj.com/content/107/4/409.2). We have more on this on our blog site, in this series: https://blogs.bmj.com/adc/category/qualitative/ We then dive down from the wards into the NICU where we wonder how to shift the clogged secretions of a grot-filled lung, and someone suggests DNAse, which sounds a lot like magic, but magic that can be evidence-based(https://adc.bmj.com/content/107/4/411). When you’ve had a listen tell us what you think, and submit your own following the instructions on the website and you too could be hearing all about yourself croaked Archi or in active conversation too. Please listen to our regular podcasts and subscribe to Apple Podcasts, Google Podcasts, Stitcher, and Spotify to get episodes automatically downloaded to your phone and computer. And if you enjoy the podcast, please leave us a review at https://podcasts.apple.com/gb/podcast/adc-podcast/id333278832

Patient Confidential - is it okay to recount patients’ stories
As healthcare professionals, we meet people from all walks of life and collect stories along the way — stories of illness and convalescence. When we hear interesting stories, there can be an urge to share them. When something bad happens, you may want to talk and offload it onto your friends and family. As we know, patient confidentiality is a core value in medicine. So what is permissible to share? Is there a way to share these stories while respecting the ethical boundaries? In this episode, the Sharp Scratch team explores the ethical considerations involved in talking and writing about patients, and discusses the popular literature genre of medical memoirs. Expert guest: Dr Matt Phillips is a sexual health consultant and a honorary clinical professor in genitourinary medicine and ethics at the University of Central Lancashire. Recommended reading: The ethics of medical memoirs. Link: https://www.bmj.com/content/367/bmj.l6270 Check us out on social media: Twitter: https://twitter.com/BMJStudent Instagram: https://www.instagram.com/bmj_student/ Facebook: https://www.facebook.com/BMJStudent/ This podcast is produced and edited by Dom Byrne and Duncan Jarvies.

Post-COVID Syndrome in Athletes. With Dr Monica Verduzco-Gutierrez. Ep #501
On this episode of the AMSSM CRN Spotlight Podcast (T: @TheAMSSM) host Dr. Jeremy Schroeder, DO, is joined by Dr. Monica Verduzco-Gutierrez (T: @MVGutierrezMD), who is serving as the AAPM&R Exchange Lecture Speaker during the 2022 AMSSM Annual Meeting. In this conversation, Dr. Verduzco-Gutierrez discusses her upcoming presentation in Austin, TX, on Post-COVID Syndrome in Athletes and address the following topics: • Defining Post-COVID Syndrome and its many potential impacts • How and why she developed a Post-COVID Recovery Clinic • Her contributions to multi-disciplinary collaborative consensus guidance statements for patients with PASC • How she generally approaches treating patients with Post-COVID Syndrome • The differences in rates and severity in Post-COVID Syndrome in athletes compared with other populations • Her advice for aspiring researchers in sport and exercise science Resources: Models of Care for Postacute COVID-19 Clinics: Experiences and a Practical Framework for Outpatient Physiatry Settings (https://pubmed.ncbi.nlm.nih.gov/34793373/) Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of breathing discomfort and respiratory sequelae in patients with post-acute sequelae of SARS-CoV-2 infection (PASC)(https://onlinelibrary.wiley.com/doi/10.1002/pmrj.12744) Multidisciplinary collaborative consensus guidance statement on the assessment and treatment of fatigue in postacute sequelae of SARS-CoV-2 infection (PASC) patients (https://onlinelibrary.wiley.com/doi/full/10.1002/pmrj.12684)

DTB turns 60! Plus: conflicts of interest, harms from nitrofurantoin and hypertension in pregnancy
In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) provide an overview of the April 2022 issue of DTB. They talk about DTB's 60th anniversary, the importance of independent scrutiny of new medicines and the need to question how medicines are licensed and used (https://dtb.bmj.com/content/60/4/50). They highlight the benefits of a comprehensive national register of conflicts of interest and discuss a study that compared a quadpill containing low doses of four antihypertensive agents with a standard dose of irbesartan (https://dtb.bmj.com/content/60/4/56). They also review a study that assessed clinicians' awareness of the harms from long-term use of nitrofurantoin (https://dtb.bmj.com/content/60/4/59) and provide an overview of an article on managing hypertension in pregnancy (https://dtb.bmj.com/content/60/4/60). The editors also look back at the very first issue of DTB that was published on 20th April 1962 (https://dtb.bmj.com/content/s1-1/1). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). Thank you for listening.

Endoscopic full-thickness plication for the treatment of PPI-dependent GERD
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Rakesh Kalapala, Senior Consultant Gastroenterologist & Therapeutic Endoscopist, Head of GI Motility Lab, Director of Endoscopy at the Center for Obesity & Metabolic Therapy, Member of the International Bariatric and Metabolic Endoscopy Committee, Asian Institute of Gastroenterology Hospitals, Hyderabad, India on the paper 'Endoscopic full-thickness plication for the treatment of PPI-dependent GERD: results from a randomised, sham controlled trial' which is published in paper copy in Gut in April 2022, and is available here: https://gut.bmj.com/content/71/4/686 Please subscribe to the Gut Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Gut Podcast iTunes page (https://podcasts.apple.com/gb/podcast/gut-podcast/id330976727).

Covid vaccine safety, Methenamine hippurate, and intersectionality
In this episode of Talk Evidence, Helen Macdonald, the BMJ’s research integrity editor is joined by Joe Ross, US research editor, and Juan Franco, editor in chief of BMJEBM, to talk about all things evidence. Joe gives us an update about covid, including new research on safety of the vaccine Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events https://www.bmj.com/content/376/bmj-2021-068373 Juan updates us on a potential new prophylactic for recurrent UTIs, Methenamine hippurate, which could be an alternative to antibiotics. Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women https://www.bmj.com/content/376/bmj-2021-0068229 Helen tells us about some research which evaluates the way in which intersecting identities combine to make students experience of medical school more difficult. Marginalized identities, mistreatment, discrimination, and burnout among US medical students https://www.bmj.com/content/376/bmj-2021-065984

First episode: Factors associated with treatment outcomes for low back pain injections
In the first episode of RAPM Focus, Editor-in-Chief Brian Sites, MD, interviews Stephen P. Cohen, MD, first author of the paper “Multicenter study evaluating factors associated with treatment outcome for low back pain injections”. This prospective study looked at 346 patients receiving one of three procedures: epidural steroid injection for sciatica, sacroiliac joint injections for axial low back pain, and facet interventions for axial low back pain. The study was designed to evaluate associations among more than two dozen demographic, clinical, and technical factors on treatment outcomes. Results found that patients with lower baseline pain scores, depressive symptomatology, and obesity experienced smaller pain reductions. Smoking and sleep deprivation were also associated with poorer outcomes. Dr. Cohen is a professor of anesthesiology and critical care medicine, neurology, physical medicine & rehabilitation and psychiatry and behavioral sciences at the Johns Hopkins School of Medicine and Uniformed Services University of the Health Sciences in Baltimore, MD. He is also chief of pain medicine and director of the Blaustein Pain Treatment Center at Johns Hopkins and director of pain research at Walter Reed National Military Medical Center. @RAPM_Online

Colon Cancer Awareness
In honor of Colon Cancer Awareness Month, Editor-in-Chief Dr. Richard McCallum and Dr. Ihsan Al Bayati, Assistant Professor of Gastroenterology at TTUHSC Paul L. Foster School of Medicine, discuss different screening modalities for colon cancer, risk factors for colon cancer, Lynch syndrome, treatment, staging, and prognosis for colorectal cancer.

Searching for genetic causes of cardiomyopathy
In this episode of the Heart podcast, Social Media Intern, Dr Andrew Perry is joined by Dr. Gasnat Shaboodien, a researcher at the University of Cape Town who studies the genetics of cardiovascular disease. If you enjoy the show, please subscribe to the podcast. Also, please consider leaving us a review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2. It helps us reach new listeners! Link to published paper: https://heart.bmj.com/content/early/2022/02/08/heartjnl-2021-320424

April 2022: consequences of armed conflicts for children; and several meanings of ‘growth’
Editor-in-Chief of the Archives of Disease in Childhood, Dr Nick Brown, and Senior Editor, Dr Rachel Agbeko, bring you the Atoms - the highlights of the April 2022 issue. They start this month by addressing the consequences of wars on children in light of the latest war in Ukraine. Read it on the Archives of Disease in Childhood website: https://adc.bmj.com/content/107/4/i Please listen to our regular podcasts and subscribe in Apple Podcasts, Google Podcasts, Stitcher and Spotify to get episodes automatically downloaded to your phone and computer. And if you enjoy the podcast, please leave us a review at https://podcasts.apple.com/gb/podcast/adc-podcast/id333278832

GOG 281: Use of Trametinib in Low-Grade Serous Cancer
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Dr. David M. Gershenson to discuss the use of trametinib in low-grade serous cancer. Dr. Gershenson is Professor and former Chair of the Department of Gynecologic Oncology and Reproductive Medicine at The University of Texas MD Anderson Cancer Center. His major focus is on the clinical and translational research of rare ovarian cancers. Highlights: Trametinib represents a new standard for the treatment of recurrent low-grade serous carcinoma of the ovary/peritoneum. The findings of GOG 281 suggest that women whose tumor harbors a MAPK mutation (KRAS, NRAS, BRAF) may have a greater probability of response to trametinib, but the results are hypothesis-generating, and further studies are needed. Importantly, trametinib should not be withheld from a woman whose tumor lacks MAPK mutations. Based on the findings of GOG 281 and preclinical studies, future trials will include combinations of a MEK inhibitor plus endocrine therapy and novel agents targeting the MAPK signaling pathway or, more specifically, RAS.

Episode 500 – The past, present and future of BJSM
In BJSM’s 500th episode, we are joined by two of the current editors, Professor Jonathan Drezner and Dr Joanna Kemp, to look ahead as well as back at the specialty in general. We discuss hot topics, the direction in which the specialty as well as the journal is heading, and we get some top tips for early career researchers and clinicians too.

Wellbeing - hot food on a night shift
The issue of food on nightshifts is a perennial grumble in the NHS, and though it might seem trivial, what does it say of an organisation if they demand their staff work when they're hungry, and what is the onward implication for that on patient care? To discuss all of these issues, we're joined by Neely Mozawala, a community specialist diabetes podiatrist, and Sahlia Saliha Mahmood-Ahmed, a gastroenterologist who have started the #24hrhotfoodfortheNHS campaign.

Great Explanations
We see patients all the time who ,more than any drug or cure, just want an explanation for their symptoms, to understand why they feel the way they do. But giving an explanation isn't necessarily straightforward, we're unsure of the diagnosis, we might worry about how the explanation might be received, or a 10 minute appointment just isn't time to go into all the details. In today's episode, we've enlisted the help of consultation skills expert, Roger Neighbour, and hear how important a great explanation is from The BMJ patient editor Amy Price. Our guests: Roger Neighbour is a retired GP and a former president of the Royal College of GPs. He has written the books on consultations skills, and teaches courses on how to put those skills into practice. Amy Price is a patient, a researcher editor for The BMJ's patient and public partnership, and a senior research scientist at Stanford School of Medicine.

Asthma In adults
Patients with asthma present with recurrent episodes of shortness of breath, chest tightness, wheezing, or coughing. Examination typically demonstrates an expiratory wheeze; however, in severe asthma there is poor air entry and the chest is silent. Lauren Eggert, Clinical Assistant Professor, Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, gives us a clinical overview of the condition. For more on asthma, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/44 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Mark Beattie's UpFront March 2022
The highlights of this edition brought to you by the Editor-in-Chief of Frontline Gastroenterology Mark Beattie. Read the UpFront of the March 2022 issue of Frontline Gastroenterology: https://fg.bmj.com/content/13/2/93 The full issue is now online: https://fg.bmj.com/content/13/2 Listen to our regular podcasts and subscribe in Apple Podcasts, Google Podcasts, Stitcher and Spotify.

Mentor's Podcast: Rene Pareja
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Dr. Rene Pareja, a gynecologist-oncologist at Astorga Oncology Clinic in Medellín and the National Cancer Institute in Bogotá, Colombia. Dr. Pareja is a reviewer for more than 20 specialty journals, an Associate Editor for IJGC, and a member of the board of directors of the International Gynecological Cancer Society (IGCS). He is the author of nine book chapters and more than 70 publications in peer-reviewed journals, and at IGCS 2021 he received an award for Community Advancement in Resource-Limited Settings. Highlights: Tips for expertise in minimally invasive surgery: (1) learn from an experienced mentor, (2) train all the time, (3) get a formal course, (4) record your surgeries. The crucial components to do surgery related research: Start to review papers, write protocols/systematic reviews, and try to work the most and tirelessly on an original project. A successful person is someone who has failed several times. Secrets and tips on life and professional career.

The clinical guideline will see you now
Medical students are taught about and examined a lot on clinical guidelines. What is best for patients overall, as recommended in guidelines, may not be appropriate for individuals. Blanket recommendations, rather than a menu of options or recommendations for shared decision making, ignore patients' preferences. So what do guidelines mean in practice? When do we deviate from them when your clinical acumen is telling you that guidelines may not be the best fit? Expert guest: Dr Liam Loftus is a GP trainee and a National Medical Director’s Clinical Fellow who has worked with the Personalised Care Institute. Recommended reading: How can tomorrow’s doctors be more caring? A phenomenological investigation. Link: onlinelibrary.wiley.com/doi/10.1111/medu.13684 Potential benefits, limitations, and harms of clinical guidelines. Link: www.bmj.com/content/318/7182/527 Check us out on social media: Twitter: twitter.com/BMJStudent Instagram: www.instagram.com/bmj_student/ Facebook: www.facebook.com/BMJStudent/ This podcast is produced and edited by Dom Byrne and Duncan Jarvies.

Editors Highlights of the April 2022 issue
Practical Neurology Editors Phil Smith and Geraint Fuller talk you through the highlights of the April 2022 issue of the journal. Read more on the PN website: https://pn.bmj.com/content/22/2/93 The full issue here: https://pn.bmj.com/content/22/2 Please subscribe to the Practical Neurology podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the Practical Neurology Podcast iTunes page (https://podcasts.apple.com/gb/podcast/pn-podcast/id942932053). Thank you for listening.

Everyone’s going to make a mistake
Medicine is complex, and as a doctor you won't always do the right thing - but you can prepare yourself for when mistakes happen, both emotionally and logistically. In this episode of Doctor Informed, Clara Munro is joined by Susanna Stamford, a patient who was on the receiving end of a mistake, which catalysed her interest in patient safety. We're also joined by Anthea Martin, from Medical Protection, who dispels some myths about saying sorry. Ayisha Ashmore returns to the pod to digest the lessons from our experts. Futher reading: The video that Susanna mentioned is available to watch on youtube bitly.com/ManagingAdverseEvents

LivingBodiesObjects: Changing the way we research
LivingBodiesObjects is a 3-year project funded by the Wellcome Trust designed to test and extend the boundaries of Medical Humanities research. Editor-in-chief of Medical Humanities, Brandy Schillace, interviews Stuart Murray, Professor of Contemporary Literatures and Film and Director of the Centre of Medical Humanities at the University of Leeds, in the UK. Read the blog with the transcription of this podcast here: https://blogs.bmj.com/medical-humanities/2022/03/17/livingbodiesobjects-with-stuart-murray. Subscribe to the Medical Humanities Podcast in all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify. If you enjoy our podcast, please consider leaving us a review and a 5-star rating on the Medical Humanities Podcast iTunes page (https://podcasts.apple.com/gb/podcast/medical-humanities-podcast/id961667204). Thank you for listening!

Care of the patient after valve intervention
In this episode of the Heart podcast, Digital Media Editor, Dr James Rudd, is joined by Dr Lynne Millar from Bart's Hospital in London. They discuss her review paper - "Care of the patient after valve intervention". If you enjoy the show, please leave us a podcast review at https://itunes.apple.com/gb/podcast/heart-podcast/id445358212?mt=2 Link to published paper: https://heart.bmj.com/content/early/2022/01/10/heartjnl-2021-319767

Neoadjuvant vs Primary Surgery: A NCDB Study with Alex Melamed
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Dr. Alex Melamed to discuss neoadjuvant versus primary surgery. Alex Melamed is a gynecologist oncologist and a health services researcher at Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian Columbia Irving Medical Center. Highlights: - The emergence of evidence supporting non-inferiority of neoadjuvant chemotherapy (NACT) compared with primary surgery for advance ovarian cancer led to increased utilization of NACT. - However, while some cancer programs in the U.S. doubled their use of NACT, others continued to use this approach infrequently. - The differential adoption of NACT by cancer programs can be viewed, and analyzed, as a natural experiment using a difference-in-differences study design. - Compared with programs that continued to use NACT infrequently, high users of NACT had similar improvements in median survival, with greater reductions in 6-month and 12-month mortality.

Solving retention to support workforce recovery
The covid-19 pandemic has stretched healthcare staff like never before. As part of the 2022 Nuffield Trust summit, The BMJ hosted a roundtable discussion looking at why workers leave the NHS and how staff wellbeing and retention can be improved. Joining us to discuss are: Kamran Abbasi, editor in chief, The BMJ Billy Palmer, senior fellow, Nuffield Trust Lucina Rolewicz, researcher, Nuffield Trust Mark Britnell, global healthcare expert and senior partner, KPMG International Neil Greenburg, consultant occupational and forensic psychiatrist, King's College London's centre for military health research Rose Penfold, National Institute for Clinical Research academic clinical fellow in geriatrics Rammya Mathew, GP and quality improvement lead for Islington GP Federation Partha Kar, diabetes consultant and NHS England's national advisor for diabetes Danny Mortimer, chief executive of NHS Employers The Nuffield Trust report, "The Long Goodbye" which was discussed in this roundtable is available here - https://www.nuffieldtrust.org.uk/resource/the-long-goodbye-exploring-rates-of-staff-leaving-the-nhs-and-social-care

Primary Survey - the highlights of March 2022, including MUST READ papers on ED exit block
Rick Body, Deputy Editor of EMJ, and Sarah Edwards, Social Media Editor of EMJ, talk through the highlights of the March 2022 edition of the EMJ. We've picked out some of the hottest, most controversial papers from this month's episodes and we're privileged to have the thoughts of the EMJ Editor in Chief, Ellen Weber. We'll discuss hot issues from the association between exit block and mortality, the 4-hour target, the prognostic importance of admitting patients to outlying wards, decision aids for traumatic brain injury and to predict hospital admission [is doctor better than computer at deciding who needs admission?] and lung ultrasound for COVID-19. Read the highlights: https://emj.bmj.com/content/39/3/165 You can subscribe to the EMJ podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest podcast every month. If you enjoy our podcast, please consider leaving us a review or a comment on the EMJ Podcast iTunes page (https://podcasts.apple.com/us/podcast/emj-podcast/id445358244). Thank you for listening!

Bacterial meningitis
Bacterial meningitis represents a life-threatening inflammation of the meninges. Elisabeth Adderson, Associate Member, St. Jude Faculty, Director, Pediatric Infectious Diseases Fellowship Program, St. Jude Children's Research Hospital, Memphis, gives an overview of the condition. For more on bacterial meningitis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/3000104 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Rural healthcare in a pandemic
In this episode of the podcast we’re going to be talking about rural healthcare - and specifically the difficulties that distance, demographics, and funding have introduced into the world’s covid-19 response. Rural regions made vulnerable by limited healthcare infrastructure, lower rates of vaccination, and opposition to government policies are the new frontlines in the pandemic, but support systems have not adjusted to the growing rural needs for health education, testing, vaccination, and treatment. Michael Forster Rothbart, Kata Karáth, and Lungelo Ndhlovu report from the US, Ecuador, and Zimbabwe

Diagnostic excellence with Hardeep Singh, Denise Connor, and Gurpreet Dhaliwal
Diagnosis is a complex categorisation task driven by mental models that reside in long term memory. Through education and experience, clinicians form scripts that encapsulate their knowledge of specific conditions and develop diagnostic schemas that structure their approach to a specific health problem. This cognitive process also intersects with systems, teamwork, and social factors that can enhance or reduce diagnostic accuracy. In this podcast, we hear about five techniques that can help with the accuracy of those mental models, and mitigate against some of the external factors which may reduce diagnostic accuracy. Our guests; Hardeep Singh trained as a GP before moving to becoming a general internist and professor of patient safety research at Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine Houston. Denise Connor is an associate professor of medicine at University of California San Francisco and a practicing internist at San Francisco Veterans Affairs Medical Center. Gurpreet Dhaliwal is a general internist at the San Francisco Veterans Affairs Medical Center, and a clinician educator.

IJGC Special Issue 2022: Radiation Oncology
In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez is joined by Dr. David Gaffney, Dr. Carien Creutzberg, and Dr. Anuja Jhingran to discuss this month's special issue on radiation oncology. Dr. Gaffney, MD, PhD, Senior Director of Clinical Research, is Professor and Vice-Chair of the University of Utah (U of U) Department of Radiation Oncology. Dr. Gaffney is a distinguished clinician and a long-standing leader in clinical research, and he is also a past president of the American Brachytherapy Society. Dr. Carien Creutzberg is Professor of Radiation Oncology at Leiden University Medical Center, the Netherlands. She specializes in research and treatment of gynecological cancers and has been initiator and principal investigator of the four PORTEC trials and the TransPORTEC consortium. She is current chair of the GCIG Endometrial Cancer Committee and past Council member of ESGO and IGCS. Dr. Anuja Jhingran is a Professor of Radiation Oncology in the Section of Gynecology at The University of Texas MD Anderson Cancer Center. She is the present treasure/secretary for IGCS. She is highly active in GCSC, GCIC, ASCO, and SGO. Her passion is to improve treatment for all women with gynecological cancer throughout the world and she does this through mentoring physicians in underserved regions throughout world. Highlights: Stereotactic body radiation therapy (SBRT) is useful in gynecological cancers. Brachytherapy improves survival in cervix cancer. Image guidance in radiation oncology decreases morbidity. Patients with small volume disease and long disease-free interval may be good candidates for SBRT. Immunotherapy can be combined with radiation therapy.

There is no pill for homelessness
There is often a debate about whether medicine is an art or a science. Our medical curriculum tends to favour the science bit, with pathophysiology of diseases and treatment algorithms dominating our learning agenda. Social determinants of health also have equal importance in influencing one’s health, but are we taught enough to address this? Timestamps: 0:00 - 3:15 Intro 3:16 - 7:19 How much do you get taught about social determinants of health at medical school 7:20 - 12:00 Do we apply what we learn in medical training about social determinants on health in actual clinical practice? 12:01 - 14:29 There is no easy one-size-fits-all managing social determinants of health 14:30 - 18:53 How do you adapt management plans according to the patient’s circumstances? 18:54 - 21:15 A medical student who has experienced homelessness before shares her insight 21:16 - 24:26 Importance of diversifying the demographic of medical students 24:27 - 28:10 The importance of empathy, compassion and being non-judgemental 29:20 - 34:20 Doctors make up the system that patients have to go through, and we can make the experience pleasant for patients 34:21 - 35:18 Vote for Lily as the next prime minister! 35:19 - 36:44 What medical students can do to address social determinants of health outside of medical capacity 36:45- 39:47 What you can do to learn more about social determinants of health in and outside of medical school 39:48 - 43:38 Final remarks Expert guest: Dr Andrew Moscrop (@andrewmoscrop on Twitter) is a GP working in a health centre for people who are homeless in Oxford and a researcher in social determinants of health. Thank you to Maz Sadler who contributed to this episode. Recommended reading: If social determinants of health are so important, shouldn’t we ask patients about them? https://www.bmj.com/content/371/bmj.m4150 *We’re looking for new panel members!* Are you a: ✅ Medical student ✅ Listener of Sharp Scratch ✅ Keen on representing the voice of medical students? In the past, the panel only consisted of medical students studying in the UK. However, remote recording meant that we can extend this opportunity to medical students in other countries. If you’re interested, please apply via the link below. We look forward to hearing from you! Apply here: https://forms.gle/QocryfkG137cWTb88 Check us out on social media: Twitter: https://twitter.com/BMJStudent Instagram: https://www.instagram.com/bmj_student/ Facebook: https://www.facebook.com/BMJStudent/ This podcast is produced and edited by Dom Byrne and Duncan Jarvies.

Golem Girl: Disability and Embodiment with Riva Lehrer
We are excited to present Riva Lehrer, artist and author, and her book GOLEM GIRL, about disability, embodiment, joy, and becoming herself. Read the blog with the transcription of this podcast here: https://blogs.bmj.com/medical-humanities/2023/03/04/podcast-with-riva-lehrer-author-of-golem-girl-a-memoir. Subscribe to the Medical Humanities Podcast in all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify. If you enjoy our podcast, please consider leaving us a review and a 5-star rating on the Medical Humanities Podcast iTunes page (https://podcasts.apple.com/gb/podcast/medical-humanities-podcast/id961667204). Thank you for listening!

Knowledge translation – moving away from ‘what’, to ‘how’ and ‘why’ with Dr Sheree Bekker. EP #499
On the podcast this week, we are thrilled to be joined by Associate Professor at the Centre for Health, Injury and Illness Prevention in Sport at the University of Bath, Dr Sheree Bekker. We have all heard the term ‘knowledge translation’, but do we really know why it is important, what this process actually involves, and how can we all start embracing it in our professional lives? Dr Bekker is a leader in this area, and we are thrilled that she has joined us to record the first in this ‘knowledge translation’ podcast series. You can find some of the resources that are mentioned in this podcast in the links below: Dr Bekker’s twitter handle https://twitter.com/shereebekker Dr Bekker’s #viral twitter thread https://twitter.com/shereebekker/status/1369972461014499331?lang=hi Anterior cruciate ligament injury: towards a gendered environmental approach https://bjsm.bmj.com/content/55/17/984 We hope you enjoyed this podcast. Get in touch with us via social media if you have any feedback or suggestions for future guests.

Rumination Syndrome, the effortless regurgitation in humans
Rumination in humans is a disorder of the gut-brain interaction affecting three percent of people worldwide. It's characterised by recurrent regurgitation without associated retching or significant nausea. Behavioural therapies are proved to be effective, with the potential to be successful at the primary care level. Dr Aditi Kumar, trainee associate editor of Frontline Gastroenterology and specialist gastroenterology registrar in the West Midlands, UK, interviews Dr Ben Disney, a Consultant Gastroenterologist at University Hospitals Coventry and Warwickshire NHS Trust, with a specialist interest on disorders of the gut-brain interaction. Also present is Dr Dipesh Vasant, a Consultant Gastroenterology and Honorary Senior Lecturer at the University of Manchester, with a specialist interest in neurogastroenterology and motility disorders. This Frontline Gastroenterology podcast discusses the recently published paper in January 2022: “Rumination Syndrome: pathophysiology, diagnosis and practical assessment” - https://fg.bmj.com/content/early/2022/01/10/flgastro-2021-101856. Listen to our regular podcasts and subscribe in Apple Podcasts, Google Podcasts, Stitcher and Spotify. If you enjoy our podcast, please rate us on your chosen platform, and leave us a review on the Frontline Gastroenterology Podcast page on iTunes: https://podcasts.apple.com/gb/podcast/fg-podcast/id942944229

Changing the perception: diversity and representation within academic Injury Prevention
In this podcast, we walk in the shoes of two PhD scholars starting out on their careers in violence and injury prevention research. Jennifer L. Thompson, MPH, and Lauren Malthaner, MPH, University of Texas, School of Public Health, describe their personal and diverse aspects of the experience they bring to their Doctoral studies. They talk about how their experiences shape their aspirations. They talk of the experience of pandemic learning and provide demonstration of how deep reflection and frank articulation of insights are such important drivers of necessary change. Please subscribe to the Injury Prevention Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify. If you enjoy our podcast, please consider leaving us a review and a 5-star rating on the Injury Prevention Podcast iTunes page (https://podcasts.apple.com/gb/podcast/injury-prevention-podcast/id942473946). Thank you for listening!

Thyroid Month: Review of Thyroid Disorders
In this episode of the JIM podcast, Editor-in-Chief Dr. Richard McCallum, speaks with Dr. Tamis Bright, the Chief of the Division of Endocrinology at Texas Tech El Paso. Last year on this podcast series, she discussed hypothyroidism. She now returns to discuss the effects, screening tools, and treatment modalities for hyperthyroidism. Dr. Tamis Bright, MD, is a Clinical Endocrinologist and Associate Professor at Texas Tech Health Sciences Paul L. Foster School of Medicine in El Paso, Texas. Additionally, she is known as an Endocrinology, Diabetes, and Metabolism specialist. Dr. Bright has more experience with Thyroid Disorders than other specialists in her area. She is affiliated with University Medical Center of El Paso, where she treats a wide variety of patients. Dr. Bright received her medical degree from Loyola University Chicago Stritch School of Medicine and has been in practice for more than 20 years.

JIM Update by the Editor-in-Chief
Editor-in-Chief Dr. Richard McCallum shares the latest details about JIM’s progress during 2021. Additionally, Dr. McCallum discusses readers’ perspectives about the journal and what we can hope to see this upcoming year from JIM.

Could a high fiber diet positively impact the gut microbiome of SLE patients?
Duane Peters from the Lupus Foundation of America interviews Professor Iryna Kulyk from Indiana University in the USA and Professor Martin Kriegel from the University of Münster in Germany and Yale University in the USA. They discuss their study, presented at the Lupus 21st Century conference in September 2021, on the influence of the consumption of resistant starch (a type of dietary fiber) on the composition of the gut microbiota of lupus patients. Access the abstract here: https://lupus.bmj.com/content/8/Suppl_2/A63.2.abstract