
Immune fitness and response to taclistamab in R/R multiple myeloma; BCR::ABL1 M244V mutation causes resistance to asciminib; HSCT and myocardial fibrosis in young patients with SCD
August 8, 202416m 59s
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Show Notes
In this week's episode we’ll discuss how immune fitness impacts response to teclistamab in relapsed/refractory multiple myeloma; learn more about a new mechanism of resistance to asciminib conferred by the BCR::ABL1 M244V mutation, and discuss the impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease.
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- Correlation of immune fitness with response to teclistamab in relapsed/refractory multiple myeloma in MajesTEC-1
- BCR::ABL1 kinase N-lobe mutants confer moderate to high degrees of resistance to asciminib
- Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease
Topics
hematologyoncologymedicalmedical researchlymphomaleukemiaCAR Tred cells