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Who Turned Up the Heat? Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Hyperpyrexia
Episode 400

Who Turned Up the Heat? Serotonin Syndrome, Neuroleptic Malignant Syndrome, and Malignant Hyperpyrexia

Beyond The Mask: Innovation & Opportunities For CRNAs · Jeremy Stanley

April 8, 20251h 3m

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Show Notes

Today we’re going to break down three life-threatening syndromes that every CRNA, anesthesia provider, and healthcare professional should know: Serotonin Syndrome, Neuroleptic Malignant Syndrome (NMS), and Malignant Hyperthermia (MH).

Though these conditions are rare, their symptoms often overlap—making quick, accurate diagnosis and intervention critical. Garry and Terry take a deep dive into the causes, symptoms, physiology, and treatment protocols for each condition, while also sprinkling in their signature humor and real-world insights.

Here’s some of what we discuss in this episode:

🧠 Understanding the overlap and differences between serotonin syndrome, NMS, and MH

💊 Medication triggers to watch out for—from SSRIs to succinylcholine

🚨 Emergency symptoms that demand immediate action

🧬 The role of genetics and pharmacology in MH

👨‍⚕️ Real-world prevention and treatment strategies for anesthesia providers

 

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