BBC Inside Science

A 17,000 year old tusk contains a remarkable story of the lifetime travels of a woolly mammoth which roamed the grasslands of Ice Age Alaska. The animal travelled 70,000 kilometres over the course of three decades before his premature death north of the Arctic Circle. The University of Alaska's Matthew Wooller tells Victoria Gill how his team pieced together the mammoth's life from isotopic clues captured in the tusk.Also in the programme: The search for storage capacity underground for all the hydrogen we'll need for a net zero carbon economy, with geoscientists Katriona Edlmann and Eike Thaysen of the University of Edinburgh.How the 1987 Montreal Protocol (which phased out CFCs) saved us from an even worse climate crisis than the one we're facing, with climate scientist Paul Young of the University of Lancester.Probiotics may protect corals from death by bleaching, with marine biologist Raquel Peixoto of King Abdullah University in Saudi Arabia.

Victoria Gill talks to climate scientist Friedericke Otto about the Intergovernmental Panel on Climate Change's new landmark report. The report this week states that the evidence for humanity's role in changing global change is now unequivocal. Dr Otto was a lead author on the chapter on extreme weather events and explains how human influence can be attributed to the increasing incidence and intensity of heat waves and heavy rainfall events.Also in the programme: Immunological evidence to support a covid vaccine booster programme in the UK, with virologist Jonathan Ball of the University of Nottingham.Faecal transplants that rejuvenated the memory and the brains of elderly mice, with neuroscientist John Cryan of University College Cork. A website for the public to report their sightings and upload their videos of ball lightning, with electrical engineer Karl Stephan of Texas State University, San Marcos.

Victoria Gill looks at the latest stories from the world of science. In this week's episode: the threat to bees from multiple pesticide exposure, how bee colonies can evolve defences against the varroa parasite, more problems for the Starliner space capsule, and what may be the oldest fossil animals yet found.

In the UK we have seen a recent fall in Covid 19 cases. Good news, but we don’t know yet if this will be sustained. The virus is now thought to be spreading predominantly amongst the under 30s, most of whom remain unvaccinated. Young adults are the demographic most likely to be vaccine hesitant or vaccine averse. Kavita Vedhara from Nottingham University discusses the delicate balancing act of managing personal choice and collective responsibility needed to persuade people to get vaccinated to help stop the spread of the virus.Forget lab rats, how about lab cats? Leslie Lyons from the University of Missouri says we’ve long neglected the genetic similarities between cats and humans. And that understanding how the diseases we share in common affect our feline friends will help with treatments for ourselves.If you take lots of medicines wouldn’t it be great to have them all in one pill? That’s the aim of Ricky Wildman’s project at Nottingham University – a personalised pill that can be 3D printed to order,And we look at the life of Nobel prize winning physicist Steven Weinberg, famed for his beautifully simple explanations of complex science and also his love of a good argument.

Proteomes, the sequences of protein within the DNA of every living thing, are notoriously difficult to model. The usual chemical methods can take months, but a new computational model using the ability of artificial intelligence to learn the complex sequences is able to predict structures within a matter of hours. Thousands of protein structure predictions are now available on a public database for anyone to access. Understanding such proteins is seen as key to treating nearly all disease. It also hold the potential for improvements in fields as diverse as increasing crop resilience to climate change and biodegrading plastic on an industrial scale. Marnie Chesterton speaks with Demis Hassabis from Deepmind which developed the protein structure prediction system, and Janet Thornton from the European Bioinformatics Institute which holds the database.Genetic engineering, the promise and perils, is the subject of a new series with Matthew Cobb on Radio 4, called Genetic Dreams, Genetic Nightmares. He tells us about the dilemmas now faced by researchers who on the one hand have the potential to send terminator genes into malaria spreading mosquitoes – but who are also aware of the huge unknowns surrounding the release of such technology.Extreme weather events are becoming more frequent. Hayley Fowler has been researching the links between weather systems, climate change and the heat and floods we are currently experiencing.And could we reduce the incidence of SARS-Cov2 with a different vaccination strategy? Julia Gog has modelled different scenarios, as the number of infections continues to rise. A strategy to target those who are mixing the most, whether socially or through their employment, may be more effective than one targeting the most vulnerable.

Epidemiologist Julian Peto is advocating mass testing as the key part of a plan to stop the virus spreading. Studies where everyone has been tested have picked up asymptomatic cases. With the addition of isolation and contact tracing this method of testing has been able to massively reduce the spread of the virus. The hope is such a coordinated scheme implemented nationally could help bring the numbers down.There’s a question over which type of test is best to use for mass testing. At the moment many of us do lateral flow tests at home. Although they give instant results their accuracy has been shown to be strongly linked to how well the tests are conducted - hence the need to back up any positive findings with the more accurate PCR test. PCR takes longer and needs sophisticated lab equipment. However a compromise could be to use RT Lamp tests, they are accurate, give results in around 20 minutes, do require a very basic lab, but without the expensive equipment of PCR. A number of RT lamp tests have now been developed for SARS-Cov2. Kevin Fong has been to see the developers of one of them, the OxLAMP test. And with the lifting of restrictions how are you going to judge your own personal risk from Covid? It’s a question that interests philosopher of science Eleanor Knox. She says government mandates on mask wearing and social distancing have allowed us to avoid tricky questions around our own potential risk from the virus and risks our own behaviour might pose to loved ones. Now there’s a lot more to think about in terms of balancing our desires to return to some semblance of normality while levels of Covid infection continue to rise. One area that’s come into sharp focus over lockdown is exercise. Some people have been unable to exercise due to Covid restrictions while others have discovered a whole new interest in moving more. A new book ‘Move’ by Caroline Williams explores the links between brain function, evolution and movement. She says staying active is a fundamental part of what makes us human.

A global project looking at the genomes of over 2 million people has found a number of distinct genetic markers which seem to either make Covid infection more likely or the symptoms more severe. Some of these markers are known to be associated with susceptibility to cancer and lung disease. However the researchers say on their own these genetic factors are not determinants of how sick people will become. Underlying health, age and sex and a range of environmental and social factors are likely more important says Andrea Ganna from Finland’s Institute of Molecular Medicine who crunched the numbers.The Royal Society Summer Exhibition has just opened. And this year its an opportunity for more people to get involved than ever before – the event is taking place online. There are a number of workshops and interactive games. We speak to a couple of the participants. Caroline Orr from Teesside University talks about research using supercomputers to make microbes produce a range of biofuels that could replace petrol and diesel, and Tony Peyton from Manchester University tells us how the electromagnetic properties of materials are bring harnessed to improve mine clearance in former war zones. And we go to another exhibition, the Royal College of Art graduate show, and ask the age old question - is it art ? Students Kukbong Kim and Bahareh Saboktakin show us their work with recycled concrete and 3d printing - which looks more like science to us.

For the first time the gene editing technique CRISPR has been used by injecting the CRISPR instructions into the bloodstream rather than directly into the affected organ. In a trial, six adult patients showed improvements after the treatment was used to prevent the expression of deformed proteins associated with a genetic disease. The hope is this method could treat a range of other genetic diseases, says Megan Molteni from Stat News.In the near future domestic gas boilers may be replaced by heat pumps. However, a district heating system in London is already installing the pumps in a scheme which should see 50% reductions in their carbon emissions. We visited the Citigen site to see how the plan would work, and discussed the potential for domestic heat pump roll out with Simon Evans from Carbon Brief. And why watermelons, wildflowers and pollinating insects can benefit from less attention. Evidence from Florida on how reducing methods associated with intensive farming chime with initiatives here in Britain to replace grass verges with banks of wildflowers. Researcher John Ternest picks up the story.

The Prime Minister has announced his desire for the UK to become a 'science superpower'. A new office within the cabinet to look at science will work alongside existing science strategy and funding structures. So far it's unclear where the responsibilities between the various science policy bodies lie. James Wilsdon, Professor of Research Policy at the University of Sheffield, helps Gaia Vince pick her way through the spaghetti of overlapping organisations and Dame Ottoline Leyser, UKRI Chief Executive, gives her her take of the impact of the reorganisation.A major new trial has been announced into the effectiveness of the drug Ivermectin for the treatment of Covid-19. There's controversy surrounding the drug, which was designed to kill parasitic worms. It showed some promise against the virus in very limited lab studies. For many reluctant to vaccinate these studies seemed to suggest an alternative way to treat the virus. However, regulatory bodies disagree. It's hoped the new study and a range of other wide scale trials will give a more rounded view on the potential if any for Ivermectin as a Covid 19 treatment. Jack Goodman from the BBC News Misinformation Unit has been looking at the controversy surrounding Ivermectin. Scientists researching it have been subject to abuse and in some countries it has been rolled out as a treatment despite the lack of evidence on its effectiveness. There have been reports of a number of cases of Black Fungus in patients with Covid-19 in India. What exactly is this unusual but life threatening fungal growth? Dr Nitin Gupta, Assistant Professor in Infectious Diseases at Kasturba Medical College in Manipal, South West India, explains why this previously rare infection is now on the rise.. Gaia Vince talks to Elena Zavala of the Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany about how she and her team have managed to extract DNA from samples of earth from the Denisovan cave in Siberia. Some years ago fragments of bone recovered from the cave revealed a new hominin species, called the Denisovans. Now DNA analysis of the layers of earth built up over hundreds of thousands of years are painting a picture of the vast variety of early people who used the cave, which included Neanderthals and early humans as well as Denisovans.

Scientists are now looking at the question of third doses of vaccines against SARS-Cov2, and this week the Cov-Boost trial was launched. It’s being run from University of Southampton and is going to be using seven different vaccines, some at half doses, in people over the age of 30 who were early recipients of their two doses. The Chief Investigator, immunologist Professor Saul Faust explains the aims of the trial.Once we've breathed the coronavirus into our lungs, how does it spread through our bodies, despite our immune defences? Remarkably, scientists have managed to film the virus in the act of infecting lung cells and spreading between them. They then added some antibodies and watched what happened. Alex Sigal of the Africa Health Research Institute tells Gaia Vince what they saw.The UK government has pledged to plant some 2 billion trees to help get us to net zero – and that’s an awful lot of plastic casing to be littering the countryside with. A team at the Institute of Making at UCL decided to look at the overall environmental impact of these tree protectors. This is quite a complicated calculation as it involves looking at the entire life cycle of the trees and the plastic, including the carbon and water and energy used. Gaia finds out from Charnette Chau, the life cycle assessment expert on the team, and Professor Mark Miodownik what they found. Across the US, people have been reporting ponds full of dead tadpoles: mass mortality events. It seems that a parasitic infection previously associated with disease in marine oyster populations, may be to blame: severe Perkinsea Infection. The big fear is that it will spread further, to places like Panama in Central America, which has seen such a drastic decline in frog populations that researchers have begun captive breeding some species as “assurance populations” to protect them from extinctions. Tom Richards, Professor of Evolutionary Genomics at the University of Oxford, reports on what he discovered when he went to Panama to see if the infection had reached its precious hoppers.

Should we be vaccinating children in the UK against SARS-Cov 2? Children are rarely seriously ill if they catch Covid but infections mean missed school, and they can pass it onto older vulnerable people. The US, Canada, Israel and Dubai are some places that are already vaccinating the under 18s and Pfizer has recently published data from a trial of its mRNA vaccine in just over 2000 12-15 year olds, showing no safety concerns. Gaia Vince discusses the issue with Professor Beate Kampmann, consultant paediatrician and Director of the Vaccine Centre at the London School of Hygiene and Tropical Medicine.Dengue fever is a widespread tropical disease caused by a virus spread by the Aedes aegypti mosquito. Until now, there’s also been no way of preventing dengue aside from trying to get rid of mosquitoes, which is pretty tricky. Gaia hears from the World Mosquito Programme’s Dr Katie Anders about some positive news from a large trial in Yogyakarta in Indonesia, where mosquitoes infected with a harmless bacteria called Wollbachia, were deliberately released. The researchers found a 77% drop in cases of dengue in the areas where the infected mosquitoes were released. Hospitalisations were 84% lower.This week the first attempt to map algal blooms globally has been released, and it also charts how blooms have changed over the last thirty years. And the news isn’t good. Henrik Enevoldsen of the UN who’s based at the University of Copenhagen, has spent thirty years studying these phenomena and he explains how the growth in aquaculture has had an impact on the rise of algal blooms in some parts of the world.Nearly twenty years after Concorde last flew, a company called Boom is promising to bring back supersonic passenger flights in the next few years. They say it’ll all be environmentally sustainable. The company has sold some new jets to the US airline United. Gaia talks to Dr Guy Gratton, an engineer and pilot at Cranfield University, about how green supersonic flight can be.

Sars Cov2, as the Covid19 coronavirus is called, probably began as the vast majority of new diseases do, when an animal virus infected a person – perhaps in a market or farm. There’s a large animal market in the city of Wuhan that sold wild as well as farmed animals, and studies have shown that different species of animals can infect each other with coronaviruses on their journey to market. But there’s also a possibility that the virus originated in one of two government laboratories in Wuhan. After all, we know that other viruses have escaped from labs, including the original Sars virus, which escaped multiple times from different Asian labs. Jonathan Ball, Professor of Virology at the University of Nottingham, discusses with Gaia Vince why the lab leak theory is again in the news.We know that obesity runs in families but because parents and children live in the same environment and eat the same food it is difficult to tease out how much of this relationship is inherited genetically. Researchers at Cambridge University have been working with the Children of the 90s cohort of people based in Bristol, and they’ve have found that a mutation in a single gene drives obesity in some families. The gene in question is called MC4R. Professor Stephen O’Rahilly, who is one of the researchers, explains that the mutation is remarkably common and has a significant impact on individuals, from an early age.Last week, researchers released the biggest and most detailed map of how matter and dark matter have spread across the universe since the Big Bang. The problem, is that the dark matter is more smoothly distributed than expected according to Einstein’s theory. Some are now saying physics is broken. Was Einstein wrong? Astrophysicist Catherine Heymans, who is a Dark Universe expert, and has just been appointed Astronomer Royal for Scotland, the first woman to hold the role, talks about the implications of the new map of dark matter and her plans to encourage the public to appreciate the night sky. For the first time figurative rock art over 4000 years old has been discovered in Scotland. Up till now all that’s been found have been marks such as cups and rings. The new images are detailed portraits of deer, with antlers, on a capstone of a burial mound, or cairn, in Kilmartin Glen on the west coast. It’s a well-studied archaeological site but the rock art hadn’t been spotted before. Gaia asked Tertia Barnett, Principal Investigator for Scotland’s Rock Art Project at Historic Environment Scotland, about who may have produced this art.

Human impact on planet earth’s plant life might be detectable several thousand years back in fossil pollen cores taken from mud columns around the world. As Suzette Flantua and Ondrej Mottl describe in a paper published in the journal Science, a rapid acceleration in the changes in pollen species goes back further than we might have expected. This matters particularly when it comes to decisions around re-wilding and re-planting areas today in the name of conservation. As they hope to build on in future work, learning more about the state of ecosystems further back into the past might prevent us making the mistake of simply recreating different types of post-agricultural situations which might not solve the problem we are trying to fix. One of the biggest impacts on the earth’s flora today is of course influenced by our meat consumption. The BBC’s Melanie Abbott has been to see a new exhibition opening at Oxford University’s Musuem of Natural History. Produced in association with the University’s Livestock, Environment and People research programme, this exhibition “Meat the Future”, seeks to raise awareness of the issues for health and the environment around eating – or not eating meat - and is open until January 2022. At the same time, a travelling interactive experience called Meat Your Persona will be moving around the UK, starting in Cardiff. And there's an online interactive questionnaire you can try from home. See the links at the bottom of the BBC Inside Science programme page. Researchers in the US are working on devices that might be able to connect with people’s brains to allow them to manipulate robotic or digital devices to regain abilities lost to disease or injury. As Dr Frank Willett and Prof Krishna Shenoy - both at Stanford University’s neural prosthetics translational laboratory - describe in the journal Nature, they have managed to create a device that allows one patient to create text using just thought. Rather than trying to guide a cursor over a keyboard, their technique works by learning which letter the patient is thinking of drawing by hand, despite being unable to wield a pen.And Jacob Dunn, associate professor at Anglia Ruskin University describes his team’s work which finds that tamarin monkeys will use the “accent” of another species when they enter its territory to help them better understand one another and potentially avoid conflict. His paper, published in the journal Behavioral Ecology and Sociobiology, describes findings in the Amazon rainforest near Manaus where a species that ordinarily use quite distinct long distance calls subtly change their call to sound more like a neighbouring species’ equivalent call when they are sharing the same area of forest. Not so much an aggressive intrusion as a polite lingua franca, it may be that the shared understanding reduces unnecessary and costly territorial fights between the two species.Presented by Victoria Gill Produced by Alex Mansfield

Vic Gill talks to scientists who have cured a vaccine-induced blood clot patient, and meets a former top F1 chief engineer who wants to transform the fuel industry.Scientists in Vienna have been continuing to look at the rare blood clots associated with the AZ Covid-19 vaccination. Paul Knoebl describes to Vic his paper describing the diagnosis and successful treatment of a patient who developed a fever whilst skiing six days after taking it. Whilst the side effect is still condsidered incredibly rare, Paul tells Vic that a relatively simple cure - after early diagnosis - should remove any lingering hesitancy of taking a vaccine.The Science Museum reopened this week with a new exhibition looking at the science of Carbon Capture. Inside Science took former Formula One technical champ Paddy Lowe to have a look round. He is interested in Carbon Capture because he has started a new company - Zero Petroleum - that aims to do nothing less than kick start a synthetic (hydrocarbon) fuel revolution. Using carbon dioxide captured from the atmosphere, he and colleague Prof Nilay Shah believe they can use renewable electricity and other feedstocks to tranform captured carbon into fuels, and create a whole new petrochemical supply that could close the loop on the industrial revolution - especially for those energy uses where batteries could not currently work, such as jet engines and heavy remote machinery.Meanwhile, up in the north east of England, Charlotte Adams of the UK's Coal Authority describes progress on measures to convert disued Coal mines to geothermal heatpumps, providing reliable steady heating for new-build homes across many parts of the UK, and taking strain off the elictircal grid.Presenter Victoria Gill Producer Alex Mansfield

Untreated wastewater "routinely released into UK rivers" is creating microplastic hotspots on riverbeds. That is the conclusion of a study in Greater Manchester, which revealed high concentrations of plastic immediately downstream of treatment works. The team behind the research concluded: untreated wastewater was the key source of river microplastic. Jamie Woodward takes Vic Gill wading in the River Tame in Greater Manchester to show some of the sites they studied, while co-author Rachel Hurley talks from Norway on the wider global questions of where microplastics get into our environment and what harm they do. The origin and location of the radioactive pollution that so devastated the lives and livelihoods of those affected by the Chernobyl disaster 35 years ago is not a mystery. But recently it has become apparent that in one small inaccessible room within the massive sarcophagus at the ill-fated power station, the nuclear fission still happening is getting slightly faster. As Neil Hyatt describes to Vic, the reason may be because the new concrete shell, unlike its predecessor, is doing a better job at keeping the rain out, and nothing to worry about for the time being. Meanwhile, Jim Smith and colleagues have been trying to demonstrate that agricultural products could help the besieged economy of surrounding areas. Using apples grown in regions where investment is illegal, they have developed a spirit drink - called Atomik - with which they hope to demonstrate a viable market outside of the Ukraine, perhaps providing jobs and export business, and maybe even useful profit with which to help the area. And finally, Dr Kim Dienes describes from Swansea the health and psychological benefits of something so many hundreds of millions of people in the world have been missing this year: a nice hug.Presenter: Vic Gill Producer: Alex Mansfield Assistant Producer: Samara Linton.

Despite being home to our early ancestors, attempts to find evidence of early burials in Africa have proved unsuccessful. That is until now. Professor María Martinón-Torres explains how findings from a 78,000-year-old Kenyan grave shed light on how our ancestors related to the dead. In keeping with the theme of clues from the past, Cardiff University academics have been studying the remains of crew who drowned on King Henry VIII’s favourite ship, the Mary Rose. As it turns out, Tudor England was more ethnically diverse than we previously thought. Victoria Gill speaks with University of Oxford researcher Dr Mehreen Datoo about a promising new malaria vaccine which was shown to be 77% effective in early trials. And Dr Nir Grossman, explains how his team at Imperial College London has been synchronising electrical pulses with rogue brain waves to treat tremors.

Now that NASA engineers have successfully flown a helicopter remotely on Mars planetary scientists are exploring how to use the technology elsewhere. Marnie Chesterton talks to Elizabeth "Zibi" Turtle, from Johns Hopkins University who is working on a mission to fly a drone, called Dragonfly, above Titan, one of Saturn's moons. A new report that has measured the state of over 200 000 of the world's glaciers has just been published. Bob McNabb of the University of Ulster explains why it's not good news as glaciers are melting at a faster pace than before. He says it could have a particular impact on people who live in low lying areas.At the start of April cases of the South African variant of SARS-Cov 2 were found in a number of London boroughs. In order to stop the further spread of these variants, a programme of surge testing was announced. It’s just come to an end and Marnie finds out from Public Health England’s regional director for London, Professor Kevin Fenton, how it worked.Birds aren’t very good at adapting to human additions to the landscape, particularly tall buildings. Could extra sonic elements - so-called acoustic lighthouses - help? From William and Mary University in Virginia, Timothy Boycott and John Swaddle joined Marnie to explain how these can make a difference.

This week has seen a huge surge in Covid- 19 in India leading to concern of a "double mutant" variant, but what do we know about this B.1.617 as it is otherwise known. It was first described in October and is now in other countries including the UK. Virologist Dr Muge Cevik looks at the emerging evidence around vaccines and new variants. Climate change threatens coffee crops so it's exciting to know that researchers have found an ancient coffee variety that is drought resistant and can tolerate higher temperatures than the highly prized Arabica coffee used to make your latte - but it wasn't easy to find. In Sierra Leone Daniel Sarmu spent 4 years searching for it and Dr Aaron Davis from Kew helped to track it down using historic samples from the Herbarium at the Royal Botanic Gardens.Clothes moths do enormous damage to our jumpers and carpets, Marnie finds out how best to protect your clothes. And we hear from Mark Miodownik about the right to repair.

The story of what we understand about the rare cases of blood clots associated with certain Covid-19 vaccines is constantly evolving. In today’s programme Professor Beverley Hunt looks at the emerging evidence.How have the restrictions due to Covid 19 affected how we grieve? Professor Claire White, an expert in grief and mourning, is investigating what it means to the grief process when the traditional ways of acknowledging death are changed.Sascha Fruholz has the unenviable task of listening to people scream all day, but he has made some surprising discoveries about which types of scream people are best able to identify.

In 2016, an accelerator physics centre called Fermilab acquired a massive circular 50 foot magnet from a lab in New York. Too big for the roads, the magnet had to take a 2000km detour via New Orleans to get to its new home. This was the start of the “muon g-2” experiment. Last week, Fermilab announced some of their results, and they don’t quite add up. UK experiment lead Professor Mark Lancaster from Manchester University tells us what they have discovered about the tiny particle that is disobeying the laws that govern how our entire universe fits together.Mountain gorillas are among the most impressive and powerful primates alive today. Living in the dense forests of eastern and central Africa, they are able to communicate with other gorillas a mile away by cupping their hands and beating their chests. Primatologist Edward Wright and colleagues have been studying male silverback gorillas and explains how gorillas use chest beating to attract potential mates and suss out competitors. And Professor Corey Bradshaw from Adelaide, South Australia sheds light on a more fearsome animal: sharks. His research has investigated the likelihood of shark attacks around the Australian coast into the future, up to 2066, and asked what would happen to those figures if everyone wore an electrical emitter that interferes with the sharks electrical senses. He finds that shark attacks are remarkably low already, but these emitters could reduce bites by up to 3000 over the next 50 years. Super fans around the world have learned to speak fluent Klingon, a fictional language originating from Star Trek. In a quest to understand the science behind these languages often dismissed as gobbledygook, Gaia Vince has been speaking to some of the linguists responsible for creating these languages. It’s time for her to relax the tongue, loosen those jaw muscles and wrap her head around the scientific building blocks embedded in language and what languages like Klingon tell us about prehistoric forms of communication.Presented by Marnie Chesterton Produced by Rory Galloway

Scientists were delighted earlier this year to find they would still have access to the EU Horizon 2020 funding and collaborations. Now, it has been revealed that membership of this group, which was previously paid for through fees to the European Union, may come directly from the science budget, at a cost of about £15 billion over the next 7 years. That’s £1-2 billion a year. Marnie Chesterton speaks with Beth Thompson, head of policy at the Wellcome Trust about the implications, and Roland Pease asks scientists working around the world how the previously announced ODA cuts are affecting their work. Native oysters help to filter coastal waters of the UK of pollutants including nitrates, while also providing habitat for other species. But their numbers have declined by 95% throughout their British range. Now, the Zoological Society of London is placing thousands of mature oysters under pontoons in marinas across the UK to let them breed, and encourage the return of the species to their former numbers. And the new coronavirus mutations that are worrying us all have been found to affect mice in experimental studies at the Pasteur Institute in France. Marnie asks if this change to the infectivity of the new variants has implications for human health and our ability to combat the virus. Presented by Marnie Chesterton Produced by Rory Galloway

The UK is reportedly halfway towards meeting its 2050 target of "net zero" carbon emissions. How did we get there and how will we achieve the next stage? ‘UK greenhouse gas emissions in 2020 were 51% below 1990 levels, according to a new Carbon Brief analysis. This means the UK is now halfway to meeting its target of “net-zero” emissions by 2050.’ Simon Evans explains his predictions from the report, outlines how we define net zero and what is required from the next few decades to ensure that the UK meets its 2050 goal. Much of Europe is attempting to replace fossil fuels, transforming transport and domestic heating to run on electrical alternatives, such as batteries and heat pumps. But where electrification isn’t possible or cost effective, such as in many homes, an alternative is still needed. Natural gas is responsible for over 30% of the UK’s total carbon emissions. Hydrogen would, theoretically, appear to be the perfect alternative, as combustion only produces water as a by product. Gaia discusses the options with hydrogen strategist, Dr Jenifer Baxter, and Dr Angela Needle of Cadent explains the pilot projects the company is carrying out to introduce 20% hydrogen into gas going into our homes. Last Friday, Fragradalsfjall began erupting for the first time in 800 years. The volcanic system is located in the West of Iceland close to the capital city of Reyjkavik. Dr Evgenia Ilynskaya of Leeds University has been out measuring the gases emitted by the eruption and she describes the experience of working on an active volcanic system.

We still know very little about exactly how the embryo forms out of a mass of dividing cells in those crucial first weeks after conception. This is also the time when many miscarriages occur, and scientists want to understand why. Couples going through IVF donate spare embryos for research and scientists are permitted to study them in a test tube, or in vitro, allowing them to grow and develop for up to 14 days. This 14 day rule is abided by globally, and it’s enshrined in the Human Fertilisation and Embryology Act in the UK. Thirty years ago no-one could keep these embryos alive for more than a few days but recently the techniques have moved on and they have been cultured for nearly 14 days. So should the 14 day rule be extended? Gaia Vince discusses this question with bioethicist professor Insoo Hyun of Case Western University and Harvard Medical School.There are other ways of studying this early development that don’t involve growing an actual embryo, and that’s by using just a few stem cells from it. These are cells that haven’t yet specialised into any type of body cell and so they have the potential to become any cell type. Researchers can grow these cells into structures that resemble embryos, although they could never survive inside a woman’s womb, and these artificial embryos aren’t subject to the 14 day rule. Gaia talks to Dr Naomi Moris of the Crick Institute in London about her work on what she calls gastruloids.Whaling was a huge industry in the 19th century, and populations of sperm whales plummeted, as hunters sought the oil in their heads that was used everywhere for lighting. The whalers who were hunting in the North Pacific kept meticulous records that have been recently made public. Biologists have been studying them, and picking out unexpected changes in the patterns of whale capture. Dr Luke Rendell of St Andrews University explains how he and his colleagues worked out that that the whales seemed to be learning from each other how to avoid the boats. A piece of intricate Ancient Greek engineering called the Antikythera mechanism, that was found by sponge divers in 1901 in the Mediterranean, has fascinated many people. Last week a team from University College London published the latest explanation of how the device worked. Science writer Jo Marchant herself became so obsessed with the mechanism that she published a book on it called Decoding the Universe and she talks to Gaia about the object and what the new research tells us about how the Greeks understood the cosmos two thousand years ago.

On Friday 5th March China published a draft for its 14th five-year plan in Beijing. The document acts as a national economic blueprint and was expected to provide an outline as to how the world’s biggest emitter of greenhouse gas emissions planned on tackling its target of reaching net zero emissions by 2060, put forward by President Xi Jinping last September. It appears that greenhouse emissions could continue to increase by 1% or more each year up until 2021. Sam Geal, acting CEO at China dialogue, explains how influential Chinese efforts are when combatting climate change. Since the late 1980s conservationists have used captive breeding to prevent the extinction of North America’s only native ferret species, the black footed ferret (Mustela nigripes). Now, an individual called WIlla, who died without leaving any offspring over 30 years ago has been cloned. Her genes represent 300% of the current genetic diversity of the species, and could help boost the chances of these animals. Dr Bridget Baumgartner works with one of the teams that took part in the successful cloning project, she describes how this novel process could bolster and prop up the genetic diversity of the dwindling population. How does one get a closer look at nutrient cycling and water temperature in marine Antarctic conditions? You could always recruit some of the local inhabitants, elephant seals! That’s exactly what Yixi Zheng at the University of East Anglia did. Her furry research assistants have revealed that surface water temperatures around the ice shelves and glaciers of Antarctica are warmer than expected in winter, and this holds implications for nutrient cycling and the productivity of the southern ocean. And finally, after an ancient rock seized the attention of the residents of Winchcombe in Gloucestershire, Professor Sara Russel discusses the rarity of finding meteors here on earth, let alone finding one early in the morning sat on your driveway. We hear what the nearly 400g of space rock that's been found this week could reveal about the origins of our solar system.Presented by Gaia Vince Produced by Rory Galloway This programme was made in association with the Open University.

With global warming continuing to increase at an alarming rate, we need all the help we can get to lock up the carbon that we’ve released into the atmosphere. Fortunately, plants have evolved to do just this, but there’s a whole class of plants that often get forgotten: the mangroves and seagrasses that grow between land and sea, which are among the planet’s most effective carbon sinks. Gaia Vince talks to Fanny Douvere, head of the marine programme at UNESCO, about its new report that shows the importance of blue carbon locked up in its marine World Heritage Sites. And Professor Hilary Kennedy, of Bangor University, explains why seagrasses are so effective at locking up carbon. Roland Pease reports on the secret journey made by one of the most valuable of human fossils, Little Foot, from Johannesburg to Oxfordshire, where it was scanned at the Diamond Light Source facility – one of the most powerful X-ray machines in the world. He talks to some of the main players about the hush hush voyage, and what they’re hoping to discover.There are few things more intriguing than an unopened letter, but what about one from 300 years ago? The Brienne Collection is a Postmaster's trunk containing more than 2000 letters sent to the Hague between 1680 and 1706, and more than 600 are still unopened. In the days before envelopes, people used elaborate folding techniques to secure letters, even tearing off a bit of paper and using that to sew the letter shut, effectively locking it. It makes reading those letters very tricky indeed, especially as antiquarians don't want to risk opening them. Instead, researchers hatched a plan to scan the letters in their untouched, still folded state, and generate a 3D image of their insides of such detail it could be used by an algorithm to unfold it virtually. David Mills from Queen Mary University London tells Gaia about how he used a microtomography scanner to peek inside the unopened letters. Presented by Gaia Vince.

On Thursday, The UN Environmental Programme published a report called Making Peace With Nature. It attempts to synthesise vast amounts of scientific knowledge and communicate “how climate change, biodiversity loss and pollution can be tackled jointly within the framework of the Sustainable Development Goals”. But it also offers clear and digestible messages that governments, institutions, businesses and individuals can act upon. Concluding BBC Inside Science’s month-long look at some of the challenges ahead of COP26 in Glasgow later this year, and its sister biodiversity meeting in China, Vic speaks with the report’s co-lead Prof Sir Robert Watson FRS and the Tyndall Centre’s Prof Rachel Warren, also a contributing author. Can all the ills of the natural world really be tackled at once?Game-shooting, for sport and food, has traditionally used the toxic metal lead for ammunition. In other parts of the world its use has been banned for the dangers to the human food chain and to the pollution in natural environments, and even deaths of wildfowl from poisoning. But not so in the UK. A year ago, as reported on Inside Science at the time, the shooting community announced a voluntary five year transition period to alternative shot materials. But researchers including profs Rhys Green and Debbie Pain from Cambridge University have discovered that a year on, little seems to have changed. Gathering game sold for food across the UK, they found that all but one bird in their sample of 180 contained lead shot. Meanwhile, up in the Himalayas, Smithsonian scientist Dr Sahas Barva was enjoying the scenery on a cold day off in 2014 when he saw and heard a tiny Goldcrest, thriving in temperatures of -10C. Wondering how such a tiny thing could keep its body insulated, he decided to investigate feathers, and utilizing the huge numbers of specimens in the Smithsonian’s collection he found some striking commonalities in the thermal properties and adaptations of birds everywhere. The higher up they live, the fluffier their coats.Presented by Victoria GillProduced by Alex MansfieldMade in association with The Open University.

On Thursday 18th Feb 2020 Nasa’s Perseverance Rover is due to touch down – gently and accurately – in the Jezero crater on Mars. Using similar nail-biting Sky Crane technology as its predecessor Curiosity, if successful it will amongst many other things attempt to fly the first helicopter in the thin Martian atmosphere, and leave small parcels of interesting samples for future missions to collect and return to earth. Unlike previous Martian landings of course, there are no mass-landing parties to be held because of Covid. So Vic Gill invites you to join her and current Curiosity and future Rosalind Franklin (ESA’s 2023 Rover) team scientists in nervously awaiting the signal of success.Dr Susanne Schwenzer was so tense during Curiosity’s final approach in 2012 that she managed to draw blood from her own hand from clutching her mobile phone too hard. BBC Inside Science expects nothing less this time round. Dr Peter Fawdon has been part of the team seand examining the landing site for ESA’s Martian lander and Rover, currently slated to launch in 2022. The project has had a complicated history, having been delayed several times. But with so much at stake, it’s worth getting right. Meanwhile, at Liverpool University, computer scientist Dr Maya Wardeh and virologist Dr Marcus Blagrove have been collaborating to see if Machine Learning and AI can help predict which mammalian species are more likely to harbour the next big coronavirus. Pitting traits and genomes, species similarities, lifestyles and ecosystems of mammals and viruses, they highlight in a paper published in Nature Communications some of the potentially most potent combinations where different coronaviruses could meet and spawn a new breakout. Not just looking for the more quotidian viral mutations the world is increasingly and unfortunately aware of, they have been looking instead for those species where something called homologous recombination between two different viruses, producing a third completely novel type, may occur. It turns out there are many possibilities beyond just bats, which are highly suspected of being the crucible in which SARS-CoV2 was smelted. To spot whatever comes next we should keep an eye on camels, rabbits, palm civets and even hedgehogs, according to the algorithm.Presented by Victoria Gill Produced by Alex MansfieldMade in Association with the Open University.

Victoria Gill and guests discuss the signs and symptoms of melting ice and anthropogenic climate warming, illicit CFC production and the racket we make in the seas. As two robotic missions from UAE and China arrive at Mars , and a third from NASA arrives next week, UK astronaut Tim Peake talks of the international collaboration in Mars research that is to come. And continuing BBC Inside Science's look at some of the issues facing COP26 delegates to Glasgow this autumn, Victoria is joined by cryosphere scientist Dr Anna Hogg,Anna studies – sometimes from space - how polar and Greenland ice sheets are melting and shifting as our climate warms. But those giant volumes of ice and concomitant rising sea levels might not be the only threat to people’s lives. It may be that the recent deadly flash flood in India was a result of a swiftly melting Himalayan glacier.The Montreal treaty - prohibiting the production of CFCs to allow the man-made polar hole in the Ozone layer identified back in the 1980s to repair - has long been cited as the classic example of an effective international agreement to protect earth's environment. But just a few years ago in 2018 Luke Western and colleagues identified not just that CFC production was suddenly and unexpectedly rising, but that it was mainly emanating from an area in eastern China. It was speculated then that their use in foams for buildings was happening illicitly on a large scale. This week, they happily announce that those emissions seem to have ceased, and that the target of a healthy ozone layer is back on track.The oceans are, since man first took to the waves, a noisy place. In a comprehensive paper published last week in the journal Science Carlos Duarte and colleagues describe how huge an impact the many anthropogenic noises that echo for miles across the sea beds have on virtually all aquatic life. He argues that it is one stressor, rather like CFCs, that we could and should take swift and effective action to address, that the time for that is ripe, and that doing so will see a swift rebound in many aquatic ecosystems. Humans are not naturally adapted to hear the noise underwater, but to illustrate the point, co-author digital artist Jana Winderen has made an acoustic demonstration for your benefit, of quite how noisy neighbours we areAlso, for listeners on BBC Sounds, the BBC's Roland Pease gives an update on where and how scientists think the covid-19 epidemic began, after a WHO team of scientists report on their recent mission to Wuhan and the infamous market. As Roland and WHO delegate Peter Daszak surmise, we still don't quite know, but it wasn't in a lab.Presented by Victoria Gill Produced by Alex MansfieldMade in Association with The Open University.

Ahead of the COP summit in Glasgow at the end of the year, this week an important study was published that attempts to enumerate the value of biodiversity in the economics of humankind. Prof Sir Partha Dasgupta's review makes it clear how essential and yet vulnerable it is.Trees play a large part in the biosystems of the planet, and replanting them is often touted as a solution to many of the carbon challeneges of the next century. But a paper and forthcoming conference hosted by Kew points out just how carefully reforestation - let alone afforestation - must be conducted.Kew tree expert Kate Hardwick tells Victoria about their 10 golden rules of planting trees.In a forest in Borneo, trees have been planted that will extract the high levels of Nickel from the local soil. It is hoped that the biomass from the trees can then be used to harvest the nickel. It is an attempt to commercialize successfully the dreams of "phytomining" - finding specific crops or traits in plants that can act to "hyperaccumulate" minerals and metals from soils. BBC Inside Science's Harrison Lewis reports how, after some intrepid botany, the idea might just now be bearing heavy fruit.But finding the plants that do some of what you want them to does not mean they should be planted just anywhere. Lulu Zhang from United Nations University in Dresden, Germany tells Victoria about the Chinese experience of a few decades ago when the Black Lotus tree seemed to be just the ticket for newly foresting huge areas of China to stabilize and neutralize soils. Unfortunately, nobody realized how thirsty the monocultured forest would be, and the thirsty trees deprived the area of much of the rainwater from humans and agriculture.Meanwhile this week scientists have published work looking at how even the noise from traffic on the roads can disrupt animal behaviour. Chris Templeton of Pacific University in Oregon has been studying how some bird's cognititve abilities can be affected. And Adam Bent describes work at Anglia Ruskin University into how crickets' mating choices can be adversely affected by recordings of the A14 near Cambridge.Presented by Victoria Gill Produced by Alex MansfieldMade in association with The Open University

A year after the first SARS-Cov2 sequences were received in the vaccine labs, Dr Alex Lathbridge and guests look into ongoing development and what next year's booster shots might be like. Prof Robin Shattock's team at Imperial College are still working on their vaccine technology - called 'Self Amplifying RNA' or saRNA. A little bit behind their well financed corporate colleagues, this week they announced that instead of pressing ahead with a phase III trial, they will instead look to developing possible boosters and alternative targets just in case more and more serious mutations happen. But as Prof Anna Blakney explains from her lab at University of British Columbia, the possibilities of saRNA don't stop with coronaviruses.Researchers in the journal PNAS report this week a new theory as to when and where dogs were first domesticated by humans, and suggest that they accompanied the first humans across the Bering straight into America. Inside Science's Geoff Marsh has a sniff around.And Dr Dean D'Souza from Anglia Ruskin University describes in Science Advances work he has done looking at certain kinds of development in children who grow up in bilingual households. His work suggests a slightly faster and keener observation of detailed changes in visual cues, and that this seems to be a trait that survives into adulthood. Presented by Alex LathbridgeProduced by Alex MansfieldMade in Association with The Open University

Reports this week talk of some BAME ethnic minorities being significantly less likely to take a covid vaccine if offered. Vittal Katikireddi and Tolullah Oni both sit on the SAGE ethnicity subgroup, and they discuss with Alex Lathbridge where the figures come from and quite what they might mean. Some of these same groups have suffered some of the worst outcomes from infection. Addressing any underlying problems that bely the figures will take a nuanced approach.Researchers in Japan and Liverpool have been investigating cat's prediliction for the herbs Catnip and Silver Vine. It turns out that there may well be a deep evolutionary reason they have evolved to love rubbing it in their fur so much: a key ingredient is a good mosquito repellent. As Professors Masao Miyazaki and Jane Hurst describe. It could help keep the mozzies away but you might end up being tailed by cats.And researcher Iestyn Woolway of the European Space Agency Climate Group, at Didcot UK, describes his work modelling the world's lakes' reaction to a warming climate over coming decades. It's not very comforting, with increased duration and intensity of what he calls "Lake Heatwaves".Presented by Alex Lathbridge Produced by Alex MansfieldMade in associataion with the Open University.Note: This podcast has been edited since the original broadcast to prevent any possible inference that the Tuskegee syphilis study involved the deliberate infection of subjects. In the Tuskegee study, African American patients who were already infected with syphilis had diagnosis and treatment deliberately withheld from them in order to observe the progression of the lethal disease over several decades (even after a perfectly simple treatment - penicillin - became available).

In the new EU-UK deal, the UK is to be an associate member of the latest EU research funding round, known as Horizon Europe. Costing around £2bn to take part, what can UK scientists now do and what has changed? UKRI CEO Otteline Leyser and the Wellcome Trust EU specialist Beth Thompson discuss ways in which UK researchers are breathing a sigh of relief.Of all the ways the UK can now diverge from the EU, DEFRA is currently holding an open consultation on whether to tweak the current GMO regulations so as not to include CRISPR-style Genetic Editing. The EU is coincidentally looking at the same issue. John Innes Centre's Janneke Balk works on making strains of wheat that have a higher level of iron for nutritional fortification. Interim head of the Roslin Institute in Scotland Bruce Whitelaw thinks developing disease resistance in farm animals is a potentially profitable area. Both agree the GMO regulations should be more tightly specified to bring clarity and opportunity for innovation. In Iceland, Kari Stefansson's company Decode Genetics analyze the genetic codes of most of the population of Iceland. This has allowed them to look at the parents, siblings, and offspring of identical twins, and identify how early genetic differences between them develop. And it's very early indeed. Given that identical twins studies are so often used to address issues surrounding the so-called Nature-vs-Nurture debate, the findings, published in the Journal Nature, are striking. Presenter by Marnie Chesterton Produced by Alex MansfieldMade in association with the Open University.

After the decision by the UK government last week to change the spacing between dosings of vaccine from the recommended 3 weeks to 12 weeks, immunologists around the world have been discussing with some urgency the wisdom of such a move. The FDA and the WHO are deeply sceptical, and the manufacturers have distanced themselves to some extent, by cautioning not to deviate from the regime tested in last year's phase III trials. The thinking behind the move is to get more people injected with a single dose in a shorter time, and that the longer wait for the second shot is worth the risk, if it means more people receive some level of protection in the short term.Clinical Epidemiologist Dr Deepthi Gurdasani and Immunoligist Prof Danny Altmann of Imperial College describe to Marnie how evidence, experience and hunch are combining in the face of the covid crisis, and quite what we know, what we don't and what we could, about this nationwide experiment. Increasingly, ecologists wanting to monitor remote areas are relying on such things as solar powered audio recorders to measure biodiversity in the sounds of the wild. But how to scrutinize years and years worth of 24 hour, multi-site recordings? Sarab Sethi and colleagues have not only been leaving solar-powered Raspberry Pi recorders out in the jungles of Borneo, they've been using machine learning techniques to look out for species and biodiversity changes from afar. You can listen to some of the Borneo work at the SAFE acoustic website (link on BBC page below).Presented by Marnie ChestertonProduced by Alex MansfieldMade in collaboration with the Open University.

As a new decade ticks over, Dr Adam Rutherford, Professor Alice Roberts and Professor Brian Cox look back on a decade of science that has transformed perceptions of our medicine, our history and our universe.From advances in genetics that have brought personalized medicine to reality, and revealed the ghosts of ancestral human species never before identified, to quantum computing lessons that hint at the nature of existence and causation throughout the universe, it has been an interesting time. New observational technologies have revealed fresh windows in time and space. And all of it has been reported by BBC Inside Science. But what of the next decade? Programme may contain traces of informed speculation, but (almost) no references to Covid.Presented by Adam Rutherford Produced by Melanie BrownMade in association with The Open University.

Nobody could have failed to notice the one story dominating the science news this year - but what about the discoveries that have been overshadowed in 2020? This week, Dr Adam Rutherford eschews all mentions of the pandemic as he invites dinosaur researcher Dr Susie Maidment, climate scientist Dr Tamsin Edwards and astrophysicist Dr Emma Chapman to share their science highlights of the year. We journey to the moon and beyond to discuss the many missions that have been blasting and grabbing bits of space rock to bring back to earth and tackle the ongoing debate about whether signs of life have been found on Venus. Back down on earth, this year could be one of, if not the, hottest years on record, with particularly high temperatures in the Arctic Circle. What might a warming world mean for ice-shelf collapse in Antarctica and how are governments responding? We discuss Joe Biden’s presidency, UK carbon emissions and what China’s recent announcements of net zero by 2060 might mean for the future of the planet. And despite limitations on travel this past year, exciting discoveries in the dinosaur world have nonetheless continued with what is believed to be the first aquatic dinosaur. The detection of soft shell eggs is also changing understandings of how dinosaurs reared their offspring.And if that wasn’t enough, Dr Adam Rutherford challenges our experts to predict what big science stories might lie on the horizon in 2021.

Dr Alex Lathbridge with your peek at the week in science.This week in the House of Commons Matt Hancock announced a new variant in the Covid virus, discovered to be spreading through the south east of the UK. As Professor Jonathan Ball of the University of Nottingham describes, there have been many slight mutations and changes to the DNA in the virus since it first emerged, and most are of no added danger. But it is important that new ones - and new combinations of them - are tracked through collaborations and networks such as COG-UK, who provide an almost real-time track of the spread of new mutations. The new one this week is of some interest as it involves a slight change to the protein of the binding area on the virus, but much lab work remains to be done,Is an angry face always an angry face? A paper in the Journal Nature this week uses Machine Learning to scan millions of videos of faces on YouTube to shed light on an old problem - the universality of facial expressions in people. The authors - working with Google - suggest that broadly speaking, in a number of contexts such as weddings and sporting events, people in much of the world tend to pull the same faces. But as Lisa Feldman Barrett - who wrote an accompanying commentary in the same journal - suggests, the way Machine Learning approaches in this area require very human perceptions to train the algorithm in the first place, means care must be taken before inferring too much.This year BBC Inside Science has been showcasing some of the mystery objects the Science Museum has uncovered in the course of moving its collections to a new home in Wroughton, Wiltshire. Jessica Bradford talks to Alex about our next one. If you have any ideas what it might be for, you can let them know by dropping a note or memory to [email protected] Presented by Alex Lathbridge Produced by Alex MansfieldMade in Association with The Open University

Dr Alex Lathbridge brings you the week in science.As the first COVID vaccines are delivered this week hastening the first glimmers of a return to normal life, is it too soon to be thinking about other future threats to humanity? James Arbuthnot, chair of a House of Lords select committee tasked to look at risk planning, and fellow committee member Martin Rees discuss their meeting this week and the assessment of the scientists invited to share their interpretations of future threats like AI, solar flares and volcanic eruptions. They are inviting evidence submissions until January 28th 2021.The Millennium Seed Bank was setup as a safety net to protect and conserve rare, threatened and useful wild plants for generations to come. As it celebrates 20 years of operation it can claim to host 16 per cent of the world’s bankable flora in its sturdy underground vaults. Alex heads down to the Royal Botanic Gardens in Wakehurst, Sussex, and meets the team coaxing seeds to life to check their viability or using cryopreserving on those seeds less convivial to being preserved. One key project is protecting farmed crops that have lost genetic diversity over time and are at risk from climate change. Through collecting and researching the wild ‘cousins’ of our modern day crops Wakehurst, Kew Gardens and its partners are researching and harnessing the resilient traits found in these less pampered crop relatives. Treezilla.org is a citizen science project designed to increase understanding of all the urban tress in the UK. Scientists, together with the public, are getting their tape measures out and cataloguing the trees to better ascertain how they influence the environment in towns and cities across the UK, to map their ages, species, sizes and health, and to help future planners to put the knowledge to work. Kate Hand is a researcher at the Open University who is looking at ways to increase our knowledge of the values trees bring to our urban environments – specifically through the lens of Milton Keynes which, it transpires, is quite the urban arboretum.

Has one of the biggest problems in biology been solved by AI? Dr Alex Lathbridge brings you the week in science.This week google's Deep Mind team presented results of their latest efforts at cracking the 50 year old problem of Protein Folding. AlphaFold has built on previous success at predicting the 3D structures of biological proteins from just knowing the sequence of amino acids of which it is made. It is a computational problem that thousands of researchers around the world have been trying to solve for decades. There are millions of different proteins doing all the work in living cells, but simply knowing what their constituent chemicals are is not enough to understand how they are shaped, and therefore how they work. Scientists are optimistic that solving the problem will herald a new era in medicine, agriculture and even sustainable recycling. Prof John Moult, founding chair of CASP - the international body that monitors progress in the field, tells of the remarkable breakthrough being discussed this week.Whilst China is trying to bring back samples of the moon this week, a much longer-lived space mission to an asteroid hopes this weekend to return samples of the earliest bits of the solar system to earth. Hyabusa 2 will complete a 6 year mission, Japanese scientists hope, this weekend when a small package of asteroid sample drops into the atmosphere above Australia on Sunday morning.And as students across the UK prepare to make their ways home for the holidays, GP Margaret McCartney and Kavita Vedhara of Nottingham University discuss some of the challenges of fast mass covid testing and false negatives.Presented by Alex Lathbridge Produced by Alex Mansfield and Melanie Brown.

Last weekend a joint European-US satellite blasted into space to begin its mission - monitoring the oceans back here on earth. Sentinel 6 Michael Freilich is one of a long line of satellites and has a striking design – appearing like a bright gold farmyard barn with a big pitched roof. Anand Jagatia speaks to Dr Ralph Cordey at Airbus Space and Defence about the latest design iteration and the technology on-board. Oceanographer Professor Penny Holiday from the National Oceanography Centre explains how Sentinel 6’s readings will enhance understanding of sea-level rises and give more detail about the currents in our oceans.We journey back to the cosmic ‘Dark Ages’, a period of time that we know hardly anything about. Dr Emma Chapman is an astrophysicist at Imperial College London who has written a book ‘First Light: Switching on Stars at the Dawn of Time’ to throw light on this illusive chapter in the history of our universe. How close are scientists to finding the first stars?With ambitious new government targets to end the sale of petrol and diesel cars by 2030 how ready are electric cars to fill the gap? One key area many companies are trying to improve are the batteries powering electric vehicles. Peter Bruce, professor of materials science from Oxford University and chief scientist at the Faraday Institution has been working on rechargeable lithium ion energy storage since the 1990s. He speaks with Anand about the current limitations and the most recent developments in battery research and development.Presented by Anand Jagatia Produced by Melanie Brown

Earlier this month, the government rolled out a pilot in Liverpool for ‘Operation Moonshot’, their proposal to spend £100 billion pounds to regularly test the entire UK population for SARS CoV 2. Anand Jagatia speaks to screening expert Dr Angela Raffle and medical test evaluator Professor Jon Deeks from the University of Birmingham. They share their concerns about the scheme and the benefits it may bring.A year ago, BBC Inside Science helped launch the Big Compost Experiment, a citizen science project run by a team at UCL. They asked the public to get involved by providing information about the matter that’s rotting in compost piles around the UK. What do people think about biodegradable plastics and what actually happens to them – do they break down like they are supposed to? Anand finds out about the results so far .from Mark Miodownik, one of the creators of this project, We travel back in time to 66 million years ago, when a massive meteorite smacked into the Gulf of Mexico bringing the reign of the dinosaurs to a cataclysmic conclusion. It was also the beginning of a new chapter in the history of life on Earth. The impact may have caused an apocalypse of earthquakes, tsunamis, volcanic eruptions and the darkness of a nuclear winter; but it may also have created a haven for new life forms to emerge. Roland Pease has been talking to two geologists, David Kring and Tim Bralower, who have found evidence for the return of life in the crater after the carnage of the meteorite strike.Presented by Anand Jagatia Produced by Melanie Brown

Scientists this week announced hopeful results in two of the big COVID-19 vaccination trials. Trudie Lang, Professor of Global Health at the Nuffield Department of Medicine, Oxford, describes some of the methodology used, what the efficacy statistic means, and how the novel approach of inserting mRNA rather than deactivated virus parts, is so exciting.Prof Charles Cockell has been investigating how bacteria might be grown in space on lumps of asteroid to extract precious minerals, and as Kim McAllister reports, his lab is itself in orbit.And it is just a few weeks since the UK, and several other countries, signed up to a set of bilateral agreements with the US called the Artemis Accords. These are an attempt to update previous outer space treaties on how countries - and indeed companies - might mine and use resources in space, given that no-one can currently legally claim sovereignty. As Dr Thomas Cheney of the Open University and Prof Jill Stuart of the LSE describe, the Accords have been greeted in certain quarters with some discord.Presented by Marnie Chesterton Produced by Alex MansfieldMade in collaboration with The Open University.

We know that children can catch the SarsCov2 virus, even though adverse side effects are incredibly rare. But what isn't clear is how likely they are to transmit the virus? If you’re a parent, are you in danger of catching the virus, maybe brought home from school by your child? A large study, using the anonymised health experiences of around 12 million adults registered with GPs in England, has just been published that explores that question. Dr Laurie Tomlinson, of London School of Hygiene and Tropical Medicine, explains the findings.On October 30th a magnitude 7 earthquake under the Aegean Sea created devastation when it struck Turkish city of Izmir. Marnie discusses the nature of the earthquake and why this area is so seismically active with Dr Laura Gregory, a geologist at Leeds University who has studied the rocks in the region. Professor Tiziana Rossetto, an expert in earthquake engineering at UCL, talks about a recent survey and intervention she carried out with the residents of Izmir to help them prepare for earthquakes.In the last of our interviews with the authors shortlisted for the Royal Society Insight Investment Science Book Prize 2020 Adam Rutherford meets the winner, Dr Camilla Pang. At the age of eight she was diagnosed with autism spectrum disorder. Struggling to understand the world around her, she went in search of a blueprint or a manual that would help her navigate the curious world of human social customs. Nearly two decades on, Camilla has produced one herself, entitled: Explaining Humans: What Science Can Teach Us about Life, Love and Relationships. Presenter: Marnie Chesterton Editor: Deborah Cohen

Marnie Chesterton presents an update on the week's science.Behind your eyes, above your mouth but below the brain, two 3cm saliva glands have been hiding since anatomy began. So reports a new study by Matthijs Valstar and Wouter Vogel of The Netherlands Cancer Institute. They describe to Marnie how they found these hitherto unnoticed glands, and importantly how knowledge of these will help people treated for head and neck cancers to get on with their lives in the future. It may be that radiotherapies have been inadvertantly destroying the glands in the past, leading to difficulties eating and breathing. Bill Bryson is the latest in BBC Inside Science's flick through 2020's Royal Society Book Prize shortlisted authors. He talks to Adam Rutherford about his work, The Body: A Guide for Occupants, and his continuing awe at its complexity.And Roland Pease reports on evidence of a return to the Dust Bowl conditions that so devastated agriculture and livelihoods in the US mid-west during the 1930s. This time, we can see the dust storms gathering from space. But that doesn't mean that intensive agriculture, extreme weather and climate change aren't combining to do what might be a re-run of some of the disastrous issues from those years.Presented by Marnie Chesterton Produced by Alex MansfieldProduced in collaboration with The Open University.

If you contracted COVID will you then be protected from further infections and illness from SARS-CoV-2 in the future? We’re starting to hear about cases of people being infected by the novel coronavirus for a second time. A handful of these cases have been published in peer reviewed journals. Nottingham University’s Professor of Virology Jonathan Ball discusses how big the problem of reinfection might be. Is it likely to be a common event which could hamper efforts to bring the pandemic under control? In the latest in our series interviewing the shortlisted authors from this year’s Royal Society Insight Investment Science Book Prize, Susannah Cahalan talks to Adam Rutherford about her investigative journalism into the scientific mystery that is mental illness. Her book ‘The Great Pretender - The Undercover Mission that Changed our Understanding of Madness’ focuses on a fundamental experiment carried out in the 1970s by renowned Stanford University Professor of Psychology David Rosenhan. His famous study was published in Science under the title ‘Being Sane in Insane Places’ and describes using ‘pseudo-patients’ to test whether they would be spotted presenting at psychiatric institutions in the US. They weren’t! His findings proceeded to shape modern psychology and psychiatry. It has been a study that Susannah, has come to find rather mysterious, with elaborate descriptions that don’t always seem to add up. Mental illness and applied neuroscience remain tricky disciplines to navigate, but Susannah has had personal experience with her own misdiagnosis of schizophrenia when she has an autoimmune brain disease.COVID does funny things to your sense of smell: Adam got a heightened sense of smell, producer Fi totally lost her sense of smell, and Inside Science reporter, Geoff Marsh – well… his sense of smell just got weird. To find out why, Geoff called in Professors Mathew Cobb, an expert on smell at the University of Manchester, and Tim Spector from Kings College London whose symptom tracker app was instrumental in getting changes to sense of smell on the symptom list for COVID.Presenter – Adam RutherfordProducers– Fiona Roberts and Andrew Luck-BakerProduced in collaboration with the Open University

From the very start of the COVID pandemic, test and trace has been the mantra. But here in the UK it was started, then abandoned as the number of cases rose too high to manage. It’s now been reintroduced and we’re all being encouraged to download the ‘NHS COVID-19’ phone app which can detect whether you’ve been near an infected person using Bluetooth technology. How have other countries around the world been managing to find, test, trace, isolate and support (FTTIS) their COVID patients? And what lessons can we learn from them? Professor Michael Hopkins at the Science Policy Research Unit (SPRU), University of Sussex Business School is part of an international team of experts in science policy, social science, medicine, epidemiology and global health that has analysed and compared national testing systems in 6 countries: Spain, South Korea, South Africa, Ireland, Germany and us, in June, July and August. Michael Hopkins told Marnie Chesterton that we all have something to learn.Over the last few weeks, we’ve been stealing a glimpse into this year’s shortlisted contenders for the annual Royal Society’s Insight Investment Science Book Prize. Linda Scott is an Emeritus Professor from the University of Oxford and a consultant to the World Bank Group on gender economics. Her book, The ‘Double X Economy - The Epic Potential of Empowering Women ’ analyses the economics of gender inequality and the hidden economics which is foundational to the more recognised and acknowledged global economics, that is, the work - much of it unpaid - done by women. Presenter – Adam RutherfordProducer – Fiona RobertsProduced in collaboration with the Open University

Claudia Hammond looks at the neuroscience behind our sense of touch. Why does a gentle touch from a loved one make us feel good? This is a question that neuroscientists have been exploring since the late 1990's, following the discovery of a special class of nerve fibres in the skin. There seems to be a neurological system dedicated to sensing and processing the gentle stroking you might receive from a parent or lover or friend, or that a monkey might receive from another grooming it. Claudia talks to neuroscientists Victoria Abraira, Rebecca Bohme, Katerina Fotopoulou and Francis McGlone who all investigate our sense of emotional touch, and she hears from Ian Waterman who lost his sense of touch at the age of eighteen. Producer: Andrew Luck-Baker

There are few images as awe-inspiring as those of the deep cosmos. Photos of the stars, galaxies, constellations and cosmic nebulae are difficult to improve on, but a new book might have done just that, by making them stereoscopic. David Eicher, Editor-in-Chief of Astronomy Magazine teamed up with astro-photographer J. P. Metsavainio, all engineered by astrophysicist and stereoscope enthusiast Dr Brian May, and they’ve created the first ever book on nebulae in 3-D, It’s called ‘Cosmic Clouds 3-D’, and is published by The London Stereoscopic Company.Have you ever thought about how fish arrive in a new pond or lake? Birds fly, other animals walk, or crawl, but fish are somewhat restricted to watery routes, and new lakes don’t necessarily have watery routes that fish can swim down. This question has been puzzling biologists for centuries. Andy Green, professor at the Doñana Biological Station in Spain has finally come up with the answer – a small number of fish eggs can survive in the guts of birds such as ducks.The Royal Society’s Insight Investment Science Book Prize shortlist was announced last week. And as every year, Inside Science is previewing each of the books, and talking to the six authors in line for this most prestigious literary prize. This week, physicist and Radio 4 brethren Jim Al-Khalili talks to Adam about how his book The World According to Physics shines a light on the most profound insights revealed by modern physics.Presenter – Adam Rutherford Producer – Fiona RobertsProduced in partnership with The Open University

The Royal Society’s Insight Investment Science Book Prize’s shortlist has just been announced. Over the next few weeks, Marnie and Adam will be chatting to the six authors in line for the prestigious prize. They’ll be getting a guided tour of ‘The Body – a Guide for Occupants’ with Bill Bryson; Discussing ‘Life According to Physics’ with Jim Al Khalili; Explaining Humans: Discovering ‘What Science Can Teach Us about Life, Love and Relationships’ with Camilla Pang; Linda Scott will be exploring ‘The Epic Potential of Empowering Women’ in her book ‘The Double X Economy’ and Susannah Cahalan will grapple with the definition of mental illness and what counts as insanity in ‘The Great Pretender: The Undercover Mission That Changed Our Understanding of Madness’. This week Gaia Vince discusses her shortlisted book Transcendence - How Humans Evolved through Fire, Language, Beauty, and Time.Last week the non-COVID news was all about how we’d failed yet again to halt the rate of biodiversity loss. The 2020 Living Planet Report showed that across the globe, the populations of mammals, birds, fish, amphibians and reptiles have declined on average by 68% since 1970. These declines, and the less well-documented loss of abundance of many plants and invertebrates, mean that our ecosystems are less diverse, less resilient and less able to provide the ecosystem services that we rely upon. Add to this that The Convention on Biological Diversity’s Fifth Global Biodiversity Outlook reports that we have failed to meet in full any of the 20 ‘Aichi Targets’ adopted by the world’s governments a decade ago. We haven’t reduced the loss of biodiversity, addressed the pressures, adequately tackled the underlying drivers or effectively facilitated the enabling conditions. We are not currently on track to meet the Convention on Biological Diversity (CBD)’s Vision of a world living in harmony with nature by 2050. If all this is making you feel depressed and despondent, be reassured that it's is not all doom and gloom, as there are still plenty of reasons for hope and optimism, according to Dr. Stuart Butchart, chief scientist at Birdlife International.The Science Museum group look after over 7.3 million items. As with most museums, the collection you see on display when you visit is only the tip of the iceberg of the entire collection. Up until now, many of the remainder (300,000 objects) has been stored in Blythe House in London. But now the collection is being moved to a purpose-built warehouse in Wiltshire. The move is a perfect opportunity for curators to see what’s there, re-catalogue long hidden gems and to conserve and care for their treasures. But during the process they have discovered a number of unidentified items that have been mislabelled or not catalogued properly in the past and some of them are just so mysterious, or esoteric, that the Science Museum needs the aid of the public to help identify them, and their uses. This week, Jessica Bradford, the keeper of collection engagement at the Science Museum is asking Inside Science listeners if they recognise, or can shed light on the possible use of the brass object with a folding fan at the end’ in the picture above. Send suggestions to Email: [email protected] or [email protected] Presenter - Marnie Chesterton Producer - Fiona Roberts

As it starts to get colder and we crank up the central heating in our homes, what will the effect be on the SARs-CoV-2 virus? As a respiratory virus like the common cold and influenza, will the coronavirus have a distinct season and will the incidence of COVID get worse in the winter? A pre-print study of over 7000 hospitalised patients across Europe and China during the early days of the pandemic plotted severity of the disease with outside temperature. In European countries as we came out of winter, into spring and then summer, Professor Gordan Lauc, lead researcher on the study, found that the severity decreased as it got warmer outside. He took outside temperature as a proxy for indoor humidity (as it gets colder, we turn on our heating, stay indoors more and the humidity in our homes, and especially our bedrooms drops). He explains to Marnie Chesterton that the subsequent drying out of our mucosal membranes in our noses and throats could be the reason we might expect things to get worse over the winter. We learn a lot about what our ancestors got up to by visualising a scene. Take Stonehenge for example, years of detective work has ascertained that 4,000 years ago, Stonehenge was made up of an outer circle of 30 standing stones called ‘sarsens’, which surrounded five huge stone arches in a horseshoe shape. There were also two circles made of smaller ‘bluestones’ – one inside the outer circle and one inside the horseshoe. But what did it sound like if you were in the middle of all these stones in prehistoric times? Last year, acoustic engineer at the University of Salford, Trevor Cox, and his team built and measured a 1:12 acoustic scale model of Stonehenge to find out. They've now completed the full analysis of those first measurements and Trevor caught up with Adam Rutherford to find out whether knowing the acoustics of a monument can tell us anything about how it might have been used. If you own a dog and like to calculate the equivalent human age of your pup, you might think that every year of your dog’s age equals 7 years in humans. So a one year old hound is 7 years old. Not so! As Geoff Marsh investigates - it’s much more complicated than that. Of course it is! Presenter – Marnie Chesterton Producer – Fiona Roberts

Vaccination has eradicated smallpox, a disease that decimated populations through the 20th century. Polio is almost gone too, and measles is no longer the pervasive childhood threat it once was. It’s clear that vaccination is our best tool to halt the threat of SARS CoV 2, and allow the return to a less restricted way of life. But it takes time to develop and test vaccines although the technologies used to create them have moved on significantly over the last few decades.Professor Jonathan Ball, a virologist at Nottingham University, talks Adam Rutherford through the several types of vaccine that are being explored in the effort to stop the coronavirus pandemic, and how they work. These include live attenuated virus vaccines that are genetically modified to appear to be SARS CoV 2 to the immune system, and RNA subunit vaccines that trick the body into recognising the virus. He discusses the way different vaccines work against disease, and how they trigger different types of immune response. Before a vaccine is approved for general use it has to pass through three trial phases, and Jonathan discusses the vaccines that are already going through phase 2 and 3 in the UK. If and when a vaccine gets approved, it needs to be produced to exacting standards and in quantities great enough to immunise the whole population. The UK Vaccine Manufacturing Taskforce was set up in May to coordinate the effort to make a vaccine. Steve Bagshaw, part of the Taskforce, explains that some vaccines have already been produced around the UK, prior to clinical approval in an effort to ensure that any approved vaccine is ready to be distributed as fast as possible to those at risk. This is unprecedented, and means the pathway to vaccine distribution could be faster than any that have gone before. Presented by Adam Rutherford Produced by Fiona Roberts and Rory Galloway